SHP-2 Activating Peptide (IRS1_pY1172 (dPEG8) pY1222)

• Background:

  It has been shown that the bisphosphorylated insulin receptor substrate 1 (IRS-1) binds to the (N) -SH2 domain of SHP-2 (PTPN11) resulting in activation of the SHP-2 enzymatic activity.

• Description:

  IRS1_pY1172 (dPEG8) pY1222 (SEQ: H2N-LN (pY) IDLDLV (dPEG8) LST (pY) -ASINFQK-amide)

• Concentration:

  100 µM

• Purity:

  > 95% (by HPLC)

• Shipping Conditions:

  -20°C

• Storage Conditions:

  Soluble in DMSO. Store at -80oC.