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SUMO2 human recombinant

SUMO2 human recombinant is available 2 times from Biovision labs

4942-1000 | SUMO2, human recombinant size: 1 mg | 1,648.77 USD

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4942-100 | SUMO2, human recombinant size: 100 ug | 279.02 USD

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Synonyms SUMO-2, Ubiquitin-like protein SMT3B, SMT3 homolog 2, Sentrin-2, HSMT3, SUMO-3, Sentrin2, SUMO2, SMT3H2, MGC117191.
Alternative_names SUMO-2, Ubiquitin-like protein SMT3B, SMT3 homolog 2, Sentrin-2, HSMT3, SUMO-3, Sentrin2, SUMO2, SMT3H2, MGC117191.
Description A substrate for deSUMOylating enzymes.
Recombinant Yes
Source E. coli
Purity by SDS-PAGE ≥95%
Assay SDS-PAGE
Biological activity Typical in vitro concentrations for conjugate formation is 10-50 µM depending on conditions.
Results 10-50 µM
Molecular Weight 11.6 kDa
Storage Temp. -80°C
Shipping Dry ice
Shelf Life 12 months
Appearance Liquid
Physical form description In 50 mM HEPES, pH 8.0, plus 150 mM NaCl, 1 mM DTT.
Background Information SUMO modification has been implicated in functions such as nuclear transport, chromosome segregation and transcriptional regulation. SUMO1 functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. Still, unlike ubiquitin which targets proteins for degradation, SUMO-2 is involved in a variety of Cellular processes, for example nuclear transport, transcriptional regulation, apoptosis, and protein stability. The active recombinant SUMO-2 is derived from the precursor pro-SUMO-2 (Accession # NM_006937). Human SUMO-2 shares 44% and 86% identity with SUMO-1 and SUMO-3 respectively. SUMOylation can occur without the requirement of a specific E3 ligase activity, where SUMO is transferred directly from UbcH9 to specific substrates. SUMOylated substrates are primarily localized to the nucleus (RanGAP-1, RANBP2, PML, p53, Sp100, HIPK2) but there are also cytosolic substrates (IκBα, GLUT1, GLUT4). SUMO modification has been implicated in functions such as nuclear transport, chromosome segregation, transcriptional regulation, apoptosis and protein stability.
Handling Centrifuge the vial prior to opening.
Usage For Research Use Only! Not to be used in humans
Properties Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Additional source Recombinants or rec. proteins
Group recombinants
Gene targetSUMO2
Short name SUMO2, recombinant
Technique Recombinant
Species Human
Alternative name SUMO2, H. sapiens recombinant
Alternative technique rec
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