LBP, recombinant LBP, recombinant lipo polysaccharide binding protein
Lipopolysaccharide-binding protein, LBP, LBP human recombinant protein, LBP human, human LBP
Elicits immune responses by presenting LPS
Purity by SDS-PAGE
Up to 2 µg/ ml LBP mediates binding of FITC-LPS (0.5µg/ml) to CD14+CHO transfectants (2 x 106/ml)
Physical form description
Lyophilized from a concentrated protein solution (1 mg/ml) containing PBS, pH 7.2
Reconstitute in 10 µl of ultra-pure distilled water. This solution can then be diluted into other aqueous buffers and stored at –20°C or –70°C for future use.
Natural LBP is a 58KD glycoprotein produced in liver. It binds at lipid A of LPS with high affinity (10-9M) and reduced the cellular LPS effects at CD14+ cells (IL1ß, IL6, TNFα). It acts as opsonin for GRAM negative cells, LPS, neutrophiles and granulocytes.
Centrifuge the vial prior to opening.
For Research Use Only! Not to be used in humans
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Recombinants or rec. proteins
LBP, mouse recombinant
lipopolysaccharide binding protein, mouse recombinant
Alternative to gene target
lipopolysaccharide binding protein, BPIFD2, LBP and IDBG-74721 and ENSG00000129988 and 3929, lipoteichoic acid binding, Extracellular, Lbp and IDBG-211482 and ENSMUSG00000016024 and 16803, BT.24181 and IDBG-642596 and ENSBTAG00000016864 and 512242