LBP, mouse recombinant

• Catalog number
  4936-10
• Price
  Please ask
• Size
  10 ug

• Synonyms
  LBP, recombinant LBP, recombinant lipo polysaccharide binding protein
• Alternative_names
  Lipopolysaccharide-binding protein, LBP, LBP human recombinant protein, LBP human, human LBP
• Description
  Elicits immune responses by presenting LPS
• Recombinant
  Yes
• Source
  CHO cells
• Purity by SDS PAGE
  ≥95%
• Assay
  SDS-PAGE
• Biological activity
  Up to 2 µg/ ml LBP mediates binding of FITC-LPS (0.5µg/ml) to CD14+CHO transfectants (2 x 106/ml)
• Molecular Weight
  64.0 kDa
• Storage Temp
  -20°C
• Shipping
  Gel pack
• Shelf Life
  12 months
• Appearance
  Lyophilized protein
• Physical form description
  Lyophilized from a concentrated protein solution (1 mg/ml) containing PBS, pH 7.2
• Reconstitution Instructions
  Reconstitute in 10 µl of ultra-pure distilled water. This solution can then be diluted into other aqueous buffers and stored at –20°C or –70°C for future use.
• Background Information
  Natural LBP is a 58KD glycoprotein produced in liver. It binds at lipid A of LPS with high affinity (10-9M) and reduced the cellular LPS effects at CD14+ cells (IL1ß, IL6, TNFα). It acts as opsonin for GRAM negative cells, LPS, neutrophiles and granulocytes.
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  LBP  
• Gene symbol
  LBP, TFCP2L1, UBP1, GRHL1, TFCP2
• Short name
  LBP, mouse recombinant
• Technique
  Recombinant, Mouse, mouses, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Host
  mouse
• Species
  Mouse, Mouses
• Alternative name
  lipopolysaccharide binding protein, mouse Rec.
• Alternative technique
  rec, murine
• Alternative to gene target
  lipopolysaccharide binding protein, BPIFD2, LBP and IDBG-74721 and ENSG00000129988 and 3929, lipoteichoic acid binding, Extracellular, Lbp and IDBG-211482 and ENSMUSG00000016024 and 16803, BT.24181 and IDBG-642596 and ENSBTAG00000016864 and 512242

Gene info

• Identity
  HGNC:6517
• Gene
  LBP
• Long gene name
  lipopolysaccharide binding protein
• Synonyms gene name
  • lipopolysaccharide-binding protein
• Synonyms
  • BPIFD2
• Synonyms name
  • BPI fold containing family D, member 2
• Locus
  20q11.23
• Discovery year
  1992-03-13
• Entrez gene record
  3929
• Pubmed identfication
  • 8432532
• RefSeq identity
  • NM_004139
• Classification
  • BPI fold containing
• VEGA ID
  OTTHUMG00000032447

Gene info

• Identity
  HGNC:17925
• Gene
  TFCP2L1
• Long gene name
  transcription factor CP2 like 1
• Synonyms gene name
  • transcription factor CP2-like 1
• Synonyms
  • LBP-9
  • CRTR1
• GenBank acession
  • AF198488
• Locus
  2q14.2
• Discovery year
  2004-01-05
• Entrez gene record
  29842
• Pubmed identfication
  • 10644752
  • 11073954
• RefSeq identity
  • NM_014553
• VEGA ID
  OTTHUMG00000131443

Gene info

• Identity
  HGNC:12507
• Gene
  UBP1
• Long gene name
  upstream binding protein 1
• Synonyms
  • LBP-1a
• GenBank acession
  • AF198487
• Locus
  3p22.3
• Discovery year
  1996-05-13
• Entrez gene record
  7342
• Pubmed identfication
  • 8114710
• RefSeq identity
  • NM_014517
• VEGA ID
  OTTHUMG00000130749

Gene info

• Identity
  HGNC:17923
• Gene
  GRHL1
• Long gene name
  grainyhead like transcription factor 1
• Synonyms gene
  • TFCP2L2
• Synonyms gene name
  • transcription factor CP2-like 2
  • grainyhead-like 1 (Drosophila)
• Synonyms
  • LBP-32
  • MGR
• Synonyms name
  • mammalian grainyhead
• GenBank acession
  • AF198489
• Locus
  2p25.1
• Discovery year
  2004-01-05
• Entrez gene record
  29841
• Pubmed identfication
  • 10644752
  • 12393799
  • 12175488
• RefSeq identity
  • NM_014552
• VEGA ID
  OTTHUMG00000151704

Gene info

• Identity
  HGNC:11748
• Gene
  TFCP2
• Long gene name
  transcription factor CP2
• Synonyms
  • CP2
  • LSF
  • LBP-1C
  • TFCP2C
• GenBank acession
  • U03494
• Locus
  12q13.12-q13.13
• Discovery year
  1994-12-15
• Entrez gene record
  7024
• Pubmed identfication
  • 8157699
• RefSeq identity
  • NM_005653
• VEGA ID
  OTTHUMG00000169621

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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