LAR/PTPRF - N Terminal GST Tag - Active Enzyme
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Catalog number
X1771E
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Price
Please ask
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Size
20 μg
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Category
Proteins & Peptides
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Long description
May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates.
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Antibody come from
Rabbit polyclonal Caspase-5 antibody was raised against a 16 amino acid peptide from the amino-terminus of human Caspase-5.
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Other description
Provided as solution in phosphate buffered saline with 0.02% sodium azide.
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Clone
not specified
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Antigen antibody binding interaction
LAR/PTPRF - N Terminal GST Tag - Active Enzyme
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Antibody is raised in
E.coli
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Antibody s reacts with
Human
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Antibody s reacts with these species
This antibody doesn't cross react with other species
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Antibody s specificity
No Data Available
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Application
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
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Antibody s suited for
Caspase-5 (NT) antibody can be used for the detection of Caspase-5 by Western blot at 1 ug/ml. Depending on cell lines or tissues used, other cleavage products may be observed.
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Storage
-20ºC
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Relevant references
1. Martinon F and Tschopp J. Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases. Cell 2004; 117:561-74._x000B__x000B_2. Kuida K, Lippke JA, Ku G, et al. Altered cytokine export and apoptosis in mice deficient in interleukin-1 β converting enzyme. Science 1995; 267:2000-3._x000B__x000B_3. Gracie JA, Robertson SE, and McInnes IB. Interleukin-18. J. Leukoc. Biol. 2003; 73:213-224_x000B__x000B_4. Martinon F, Burns K, and Tschopp J. The inflammasome: a molecular platform triggering activation of the inflammatory caspases and processing of proIL-1_. Mol. Cell. 2002; 10:417-26.
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Protein number
see ncbi
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Warnings
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
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Description
Enzymes are cleaving the substrate. If the substrate is DNA they are called restriction enzymes. Activating enzymes will cut off the domain that is biological active to become functional.
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Gene target
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Gene symbol
PTPRF, MGST3
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Short name
LAR/PTPRF - N Terminal GST Tag - Active Enzyme
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Technique
Enzyme, enzymes, Tags
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Isotype
not specified
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Label
unlabeled
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Alternative name
LAR/protein tyrosine phosphatase, receptor classification, F - N Terminal GST detection labelled - functionnal Enzyme
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Alternative technique
enzymes
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Alternative to gene target
protein tyrosine phosphatase, receptor type, F, BNAH2 and LAR, PTPRF and IDBG-97490 and ENSG00000142949 and 5792, protein complex binding, Plasma membranes, Ptprf and IDBG-180768 and ENSMUSG00000033295 and 19268, PTPRF and IDBG-640420 and ENSBTAG00000000253 and 512072
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Gene info
Gene info
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