G-CSF, murine recombinant

  • Catalog number
    4095-10
  • Price
    Please ask
  • Size
    10 ug
  • Synonyms
    Granulocyte Colony-Stimulating Factor, CSF-3, MGI-1G, GM-CSF β, pluripoietin
  • Alternative_names
    Granulocyte Colony-Stimulating Factor, CSF-3, MGI-1G, GM-CSF β, pluripoietin
  • Description
    A cytokine that stimulates the bone marrow to produce granulocytes and stem cells
  • Recombinant
    Yes
  • Source
    E. coli
  • Purity by SDS PAGE
    ≥98%
  • Assay
    SDS-PAGE
  • Purity
    ≥98%
  • Biological activity
    The ED₅₀ as determined by the dose-dependent stimulation of the proliferation of murine M-NFS-60 cells is < 0.05 ng/ml, corresponding to a specific activity of > 2 x 10⁷ units/mg.
  • Molecular Weight
    19.0 kDa
  • Storage Temp
    -20°C
  • Shipping
    Gel pack
  • Shelf Life
    12 months
  • Appearance
    Lyophilized protein
  • Physical form description
    Sterile filtered and lyophilized from 5 mM NaCitrate, pH 4.0
  • Reconstitution Instructions
    Reconstitute in H₂O to a concentration of 0.1-1 mg/ml. The solution can then be diluted into other aqueous buffers and store at 4°C for 1 week or –20°C for future use.
  • Background Information
    G-CSF is a potent stimulator of bone marrow cells, especially those of neutrophil lineage. In addition, G-CSF can enhance the survival and activate the immunological functions of mature neutrophils. Murine G-CSF is a 19.0 kDa protein containing 179 amino acid residues.
  • Handling
    Centrifuge the vial prior to opening.
  • Usage
    For Research Use Only! Not to be used in humans
  • Gene
    Granulocyte-colony stimulating factor (G-CSF or GCSF), also known as colony-stimulating factor 3 (CSF 3), is a glycoprotein that stimulates the bone marrow to produce granulocytes and stem cells and release them into the bloodstream. Functionally, it is a cytokine and hormone, a type of colony-stimulating factor, and is produced by a number of different tissues. The pharmaceutical analogs of naturally occurring G-CSF are called filgrastim and lenograstim.
  • Additional source
    Recombinants or rec. proteins
  • Group
    recombinants
  • Gene target
    G-CSF   murine  
  • Gene symbol
    CSF3, IGHV3-71, HLA-G, NCAPG, FOLR3, CSF2, SNRPG, GNAO1, CSF1, SFTA2
  • Short name
    G-CSF, murine recombinant
  • Technique
    Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
  • Alternative name
    G-CSF, murine Rec.
  • Alternative technique
    rec
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    immunoglobulin heavy variable 3-71 (pseudogene)
  • Synonyms gene
  • Synonyms gene name
    • immunoglobulin heavy variable 3-71
    • immunoglobulin heavy variable 3-G pseudogene (provisional)
    • immunoglobulin heavy variable 3-G (provisional)
    • immunoglobulin heavy variable 3-71 pseudogene
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    2000-04-04
  • Entrez gene record
  • RefSeq identity
  • Classification
    • Immunoglobulin heavy locus at 14q32.33
  • VEGA ID
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    G protein subunit alpha o1
  • Synonyms gene name
    • guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
  • Synonyms
  • Locus
  • Discovery year
    1988-04-24
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • G protein subunits alpha, group i
    • MicroRNA protein coding host genes
  • VEGA ID
Gene info
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: The initial culturing of cells derived directly from fresh TISSUES.
  • Tree numbers
    • E01.370.225.500.223.500
    • E05.200.500.265.500
    • E05.242.223.500
    • E05.481.500.249.500
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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