Synonyms
Monocyte Chemotactic Protein-1, CCL2, MCAF
Alternative_names
Monocyte Chemotactic Protein-1, CCL2, MCAF, Monocyte chemoattractant protein 1, Monocyte secretory protein JE, Small-inducible cytokine A2
Description
Chemoattractant for monocytes and basophils
Recombinant
Yes
Source
E. coli
Purity by SDS-PAGE
≥98%
Assay
SDS-PAGE
Purity
≥98%
Biological activity
Determined by its ability to chemoattract human monocytes using a concentration range of 10-100 ng/ml.
Results
10-100 ng/ml.
Molecular Weight
14.0 kDa
Storage Temp.
-20°C
Shipping
Gel pack
Shelf Life
12 months
Appearance
Lyophilized protein
Physical form description
Sterile filtered and then lyophilized with no additives. The protein may appear as a haze or film which is difficult to see at the bottom of the vial.
Reconstitution Instructions
Reconstitute in H₂O to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other buffered solutions and stored at 4°C for 1 week or –20°C for future use.
Background Information
Macrophage/monocyte chemoattractant protein-1 (MCP-1) plays an important role in the inflammatory response of blood monocytes and tissue microphages. Recombinant rat MCP-1 is a 14.0 kDa protein containing 125 amino acid residues.
Handling
Centrifuge the vial prior to opening.
Usage
For Research Use Only! Not to be used in humans
About
Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
Latin name
Rattus norvegicus
Additional source
Recombinants or rec. proteins
Group
recombinants
Gene targetMCP-1
MCAF
Short name
MCP-1 (MCAF) recombinant
Technique
Recombinant
Host
Rat
Species
Rat
Alternative name
MCP-1 (MCAF), rat recombinant
Alternative technique
rec
