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PINK1 (N-terminal) - Blocking Peptide

PINK1 (N-terminal) - Blocking Peptide is available 1 time from Nordc labs

X2774B | PINK1 (N-terminal) - Blocking Peptide size: 50 μg | 186.08 USD

Catalog number X2774B
Supplier nordc
Price 186.08 USD
Size 50 μg
1. Gene info
Identity 14581
Gene PINK1
Long gene name PTEN induced putative kinase 1
Synonyms gene
  • PARK6
Synonyms gene name
  • Parkinson disease (autosomal recessive) 6
GenBank acession
  • AB053323
Locus 1p36.12
Discovery year 2001-02-08
Entrez gene record 65018
Pubmed identfication
  • 11494141
  • 15349860
RefSeq identity
  • NM_032409
Classification
  • Parkinson disease associated genes
Havana BLAST/BLAT OTTHUMG00000002841
Locus Specific Databases
  • Parkinson's disease Mutation Database
2. Gene info
Identity 38872
Gene PINK1-AS
Long gene name PINK1 antisense RNA
Synonyms gene
  • PINK1-AS1
Synonyms gene name
  • PINK1 antisense RNA 1 (non-protein coding)
  • PINK1 antisense RNA (non-protein coding)
Synonyms
  • FLJ00387
  • PINK1AS
  • naPINK1
GenBank acession
  • AK090466
Locus 1p36.12
Discovery year 2010-08-19
Pubmed identfication
  • 17362513
Classification
  • Long non-coding RNAs (published)
Havana BLAST/BLAT OTTHUMG00000002840
Category Proteins & Peptides
Long description This peptide is the immunogen used to make Cat # X2759P. _x000B__x000B_Protects against mitochondrial dysfunction during cellular stress, potentially by phosphorylating mitochondrial proteins. Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy). It is necessary for PARK2 recruitment to dysfunctional mitochondria to initiate their degradation. Defects in PINK1 are the cause of Parkinson disease type 6 (PARK6). A neurodegenerative disorder characterized by parkinsonian signs such as rigidity, resting tremor and bradykinesia. A subset of patients manifest additional symptoms including hyperreflexia, autonomic instability, dementia and psychiatric disturbances. Symptoms show diurnal fluctuation and can improve after sleep.
Antibody come from Recombinant protein derived from the carboxy terminus of the calreticulin protein fused to KLH.
Other description Provided as solution in phosphate buffered saline with 0.08% sodium azide.
Clone not specified
Antigen-antibody binding interaction PINK1 (N-terminal) - Blocking Peptide
Antibody is raised in see techfile
Antibody's reacts with Blocking Peptide to Cat # X2759P
Antibody's reacts with these species This antibody doesn't cross react with other species
Antibody's specificity No Data Available
Application Blocking Peptide
Antibody's suited for Antibody can be used for Western blotting (1:1000-1:5000 dilution) and immunofluorescence (1:50 dilution). Optimal concentration should be evaluated by serial dilutions. Suitable for use against recombinant proteins conjugated to OVA, GST, His tags and other.
Storage -20ºC
Relevant references 1. Kageyama, S., et al. 'Urinary calreticulin in the diagnosis of bladder urothelial carcinoma.' Int. J. Urol. 2009, 16, 481-486_x000B__x000B_2. Silerova, M., et al. 'Characterization, molecular cloning and localization of calreticulin in Eisenia fetida earthworms.' Gene 2007, 397, 169-177_x000B__x000B_3. Souto-Padron, T., et al. 'Immunocytochemical localisation of calreticulin in Trypanosoma cruzi.' Histochem. Cell Biol. 2004, 122, 563-569
Protein number see ncbi
Warnings This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
Test You can block the antibody by the specific target amino acid sequence of peptide.
Properties blocking peptide
Description Peptides short amino acid chains or epitopes or blocking antagonists. The shortest peptides are dipeptides, consisting of 2 amino acids joined by a single peptide bond, followed by tripeptides, tetra peptides, ... till polypeptides that are long, continuous, and unbranched synthetic peptide chains. These biological oligomers and polymers can be Solid-phase peptide synthesis (SPPS), or in continue produced for custom peptide synthesis projects. The High-efficiency solid phase peptide synthesis (HE-SPPS) is give very low production costs.
Gene targetPINK1
Short name PINK1 (N-terminal) - Blocking Peptide
Technique blocking peptide, Blocking, peptide
Alternative name phosphatase and tensin homolog induced putative kinase 1 (N-terminal) - inhibiting short protein sequence
Alternative technique control
Alternative to gene target PTEN induced putative kinase 1, PINK1 and IDBG-92922 and ENSG00000158828 and 65018, transferase activity, nuclei, Pink1 and IDBG-199773 and ENSMUSG00000028756 and 68943, PINK1 and IDBG-645657 and ENSBTAG00000006084 and 510683
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