Anti-APAF1 (aa12-28)

  • Catalog number
    MBS223169
  • Price
    Please ask
  • Size
    50ug
  • Alternative name1
    Anti-RABBIT ANTI APAF1 (aa12-28)
  • Alternative name2
    RABBIT ANTI APAF1 (aa12-28)
  • Alternative name3
    Lapin ANTI APAF1 (aa12-28)
  • Alternative name4
    APAF1
  • Alternative name5
    N/A
  • Other names
    apoptotic protease-activating factor 1 isoform b; Apoptotic protease-activating factor 1; apoptotic protease-activating factor 1; apoptotic peptidase activating factor 1; N/A
  • Gene name
    APAF1
  • Gene name synonims
    N/A
  • Other gene names
    APAF1; APAF1; CED4; APAF-1; KIAA0413; APAF-1
  • Category
    Antibodies
  • Clonality
    Polyclonal
  • Immunoglobulin isotype
    Polyclonal IgG
  • Clone
    Polyclonal antibody
  • Host organism
    Rabbit
  • Species reactivity
    Human
  • Specificity and cross reactivity
    APAF1 Apaf1 (Apoptosis protease activating factor 1) is the mammalian homologue of the CED-4 cell death protein in C. Elegans. Apaf1 binds to cytochrome C and caspase-9 leading to caspase-9 activation, resulting in the beginning of the proteolytic cascade characteristic of apoptosis. Apaf1 can also associate with caspase-4 and caspase-8. MBS221594 recognises a 130kD band in Western blots.
  • Purification method
    N/A
  • Form Appearance
    Purified (Purified IgG - liquid)
  • Concentration
    IgG concentration 0.5 mg/ml
  • Storage and shipping
    Store at +Store productone at +4 degrees Celsius. or productone should be stored at -20 degrees Celsius. if preferred. productone should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should productone contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of dispatch.
  • Tested for
    Immunohistology - Paraffin (IHC), Western Blot (WB)
  • Description
    productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.
  • Advisory
    In order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
  • Additional description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
  • Gene target
    APAF1   aa12-28  
  • Gene symbol
    APAF1
  • Short name
    Anti-APAF1 (aa12-28)
  • Technique
    anti-, anti, antibody to, antibodies
  • Alternative name
    Antibody toAPAF1 (aa12-28)
  • Alternative technique
    antibodies
  • Alternative to gene target
    apoptotic peptidase activating factor 1, APAF-1 and CED4, APAF1 and IDBG-52364 and ENSG00000120868 and 317, ADP binding, nuclei, Apaf1 and IDBG-185032 and ENSMUSG00000019979 and 11783, APAF1 and IDBG-636787 and ENSBTAG00000021661 and 537782
Gene info
  • Identity
  • Gene
  • Long gene name
    apoptotic peptidase activating factor 1
  • Synonyms gene name
    • apoptotic protease activating factor
    • apoptotic peptidase activating factor
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1998-01-20
  • Entrez gene record
    317
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Apoptosome
    • WD repeat domain containing
    • Caspase recruitment domain containing
  • VEGA ID
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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