COP1, NT (CARD16, COP, COP1, Caspase recruitment domain-containing protein 16, CARD only domain-containing protein 1, Caspase-1 inhibitor COP, Pseudo interleukin-1 beta converting enzyme)[COP1]

• Catalog number
  MBS644935
• Price
  Please ask
• Size
  NA

• Products_type
  Antibody
• Reactivity
  Human
• Description
  Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways. Enzymes are cleaving the substrate. If the substrate is DNA they are called restriction enzymes. Activating enzymes will cut off the domain that is biological active to become functional. Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.

• Gene target
  COP1   CARD16   COP   COP1   Caspase   recruitment   domain   protein   CARD   only   domain   protein   Caspase-1   inhibitor   COP   Pseudo   interleukin-1   beta   converting   [COP1]  
• Gene symbol
  CARD16, COP1-DT, COPB2, COP1, COPG2, COPA, COPE
• Short name
  COP1, NT (CARD16, COP, COP1, Caspase recruitment domain- protein 16, CARD only domain- protein 1, Caspase-1 inhibitor COP, Pseudo interleukin-1 beta converting enzyme)[COP1]
• Technique
  Enzyme, enzymes
• Host
  Rabbit
• Alternative name
  COP1, NT (caspase recruitment domain family, member 16, COP, COP1, caspase recruitment domain-containing protein 16, CARD only domain-containing protein 1, caspase-1 suppressor COP, Pseudo Interleukin-1 b converting enzyme)[COP1]
• Alternative technique
  enzymes
• Alternative to gene target
  caspase recruitment domain family, member 16, CARD16 and IDBG-69692 and ENSG00000204397 and 114769, cysteine-type endopeptidase inhibitor activity, multiple

Gene info

• Identity
  HGNC:33701
• Gene
  CARD16
• Long gene name
  caspase recruitment domain family member 16
• Synonyms gene name
  • caspase recruitment domain family, member 16
• Synonyms
  • COP1
  • COP
  • PSEUDO-ICE
  • LLID-114769
• Locus
  11q22.3
• Discovery year
  2008-09-15
• Entrez gene record
  114769
• Pubmed identfication
  • 11432859
  • 11536016
• Classification
  • Caspase recruitment domain containing
• VEGA ID
  OTTHUMG00000166157

Gene info

• Identity
  HGNC:55666
• Gene
  COP1-DT
• Long gene name
  COP1 divergent transcript
• Locus
  1q25.2
• Discovery year
  2021-06-30
• Classification
  • Divergent transcripts

Gene info

• Identity
  HGNC:2232
• Gene
  COPB2
• Long gene name
  COPI coat complex subunit beta 2
• Synonyms gene name
  • coatomer protein complex, subunit beta 2 (beta prime)
  • coatomer protein complex subunit beta 2 (beta prime)
• Synonyms
  • beta'-COP
  • betaprime-COP
• Synonyms name
  • coatomer protein complex subunit beta prime
• GenBank acession
  • BC000326
• Locus
  3q23
• Discovery year
  1999-04-23
• Entrez gene record
  9276
• Pubmed identfication
  • 9858824
• RefSeq identity
  • NM_004766
• Classification
  • WD repeat domain containing
  • COPI coat complex
• VEGA ID
  OTTHUMG00000159959

Gene info

• Identity
  HGNC:17440
• Gene
  COP1
• Long gene name
  COP1 E3 ubiquitin ligase
• Synonyms gene
  • RFWD2
• Synonyms gene name
  • ring finger and WD repeat domain 2
• Synonyms
  • FLJ10416
  • RNF200
  • FAP78
  • CFAP78
• Synonyms name
  • constitutive photomorphogenic protein 1 (Arabidopsis)
• GenBank acession
  • AK001278
• Locus
  1q25.1-q25.2
• Discovery year
  2005-01-13
• Entrez gene record
  64326
• Pubmed identfication
  • 10395541
• RefSeq identity
  • NM_022457
• Classification
  • Small nucleolar RNA protein coding host genes
  • WD repeat domain containing
  • Cilia and flagella associated
  • Ring finger proteins
• VEGA ID
  OTTHUMG00000034986

Gene info

• Identity
  HGNC:2237
• Gene
  COPG2
• Long gene name
  COPI coat complex subunit gamma 2
• Synonyms gene name
  • coatomer protein complex, subunit gamma 2
• Synonyms
  • 2-COP
• Synonyms name
  • coat protein, nonclathrin, gamma-2-cop
• GenBank acession
  • AF157833
• Locus
  7q32.2
• Discovery year
  1999-12-17
• Entrez gene record
  26958
• Pubmed identfication
  • 10556286
  • 10995575
• RefSeq identity
  • NM_012133
• Classification
  • Clathrin/coatomer adaptor, adaptin-like, N-terminal domain containing
  • COPI coat complex
• VEGA ID
  OTTHUMG00000155364

Gene info

• Identity
  HGNC:2230
• Gene
  COPA
• Long gene name
  COPI coat complex subunit alpha
• Synonyms gene name
  • coatomer protein complex, subunit alpha
• Synonyms
  • HEP-COP
• Synonyms name
  • proxenin
  • xenin
• GenBank acession
  • U24105
• Locus
  1q23.2
• Discovery year
  1996-11-15
• Entrez gene record
  1314
• Pubmed identfication
  • 8647451
• RefSeq identity
  • NM_004371
• Classification
  • WD repeat domain containing
  • COPI coat complex
  • Receptor ligands
• VEGA ID
  OTTHUMG00000033111
• Locus Specific Databases
  • LRG_1336

Gene info

• Identity
  HGNC:2234
• Gene
  COPE
• Long gene name
  COPI coat complex subunit epsilon
• Synonyms gene name
  • coatomer protein complex, subunit epsilon
• Synonyms
  • epsilon-COP
• GenBank acession
  • AJ131182
• Locus
  19p13.11
• Discovery year
  1999-09-28
• Entrez gene record
  11316
• Pubmed identfication
  • 10469566
• RefSeq identity
  • NM_007263
• Classification
  • COPI coat complex
• VEGA ID
  OTTHUMG00000183052

MeSH Data

• Name
  Models, Chemical
• Concept
  Scope note: Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.
• Tree numbers
  • E05.599.495

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