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Spoligotyping Membrane

Spoligotyping Membrane is available 1 time from Ocimum biosolutions labs

IM9702 | Spoligotyping Membrane size: 1 EA | 1,686.64 USD

Catalog number IM9702
Price 1,686.64 USD
Size 1 EA
1. Gene info
Identity7416
GeneMTATT
Synonyms gene name
  • membrane attachment site
Discovery year1989-10-11
Availability Please contact Gentaur/Genprice to check the latest availability
Ordering Current price is for Diagnostics labs. Special -16% discount for Research Institutes. For ordering please contact us at +32 16 58 90 45
Technical file Please contact us to request the current datasheet or security datasheet
Description Associated membrane protein types are lipopolysaccharide selective barriers. Biological membranes include cell membranes, outer coverings of cells or organelles that allow passage of certain proteins and nuclear membranes, which cover a cell nucleus; and tissue membranes, such as mucosae and serosae. 
Test A rapid, polymerase chain reaction (PCR)-based method for genotyping strains of the Mycobacterium tuberculosis complex (MTB). Spoligotyping data can be represented in absolute terms (digitally), and the results can be readily shared among laboratories, thereby enabling the creation of large international databases. Since the spoligotype assay was standardized more than 10 yr. ago, tens of thousands of isolates have been analyzed, giving a global picture of MTB strain diversity. The GENTAUR method is highly reproducible and has been developed into a high-throughput assay for large molecular epidemiology projects. In the United States, spoligotyping is employed on nearly all newly identified culture-positive cases of tuberculosis as part of a national genotyping program. The strengths of this method include its low cost, its digital data results, the good correlation of its results with other genetics markers, its fair level of overall differentiation of strains, its high-throughput capacity, and its ability to provide species information. However, the method's weaknesses include the inability of spoligotyping to differentiate well within large strain families such as the Beijing family, the potential for convergent evolution of patterns, the limited success in improving the assay through expansion, and the difficulty in obtaining the specialized membranes and instrumentation
Gene targetMembrane
Short name Spoligotyping
Technique Spoligotyping
Alternative name Spoligotyping Membrane
Alternative technique mycobacteria
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