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Human Recombinant Ubiquitin K29R

Human Recombinant Ubiquitin K29R is available 0 time from Biovision labs

Background Ubiquitin is a small polypeptide that can be conjugated via its C-terminus to amine groups of lysine residue on target proteins. This conjunction is referred to as monoubiquitylation. Additional ubiquitin moieties can be subsequently conjugated to this initial ubiquitin, utilizing any one of the seven lysine residues on the surface of ubiquitin. The formation of these ubiquitin chains is referred to as polyubiquitylation. This tag-free recombinant form of human ubiquitin is engineered to have a single substitution of arginine for lysine at position 29. Covalent attachment of ubiquitin to other proteins serves various functions, but its major role is to target cellular proteins for destruction. Cellular components that activate, transfer, remove, or simply recognize ubiquitin number in the hundreds, perhaps even in the thousands. In light of this complexity the ubiquitin pathway is ideal for a systems biology approach. Ubiquitin plays a very important role in regulated non-lysosomal ATP dependent protein degradation. The Ub-proteasome proteolytic pathway, which is a complex process, is implicated to be of great importance for regulating numerous cellular processes.
Concentration 4 mg/ml
Molecular weight 8.592 kDa
Synonym Human Recombinant Ubiquitin-K29R
NCBI gene number 6233
NCBI gene RPS27A
Gene source Human
NCBI number P62979
Recombinant Yes
Source E. Coli
Purification ≥95%
Tested applications RP-HPLC, N/A
Level of endotoxin N/A
Tested activity N/A
Biological activity N/A
Reesults N/A
Binding ability N/A
Unit N/A
Storage condition -80°C
Shipping under gel pack
Physical appearance Liquid
Physical properties 4 mg/ml in 20 mM Tris, pH 7.5, 0.15 M NaCl and 10% glycerol.
How to reconstitute N/A
Aa sequence N/A
Before use Centrifuge the vial prior to opening.
Notes For Research Use Only! Not to be used in humans
Properties Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Additional source Recombinants or rec. proteins
Group recombinants
Gene targetUbiquitin-K29R
Short name Recombinant Ubiquitin-K29R
Technique Recombinant
Species Human
Alternative name H. sapiens recombinant Ubiquitin-K29R
Alternative technique rec
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