100ug-Anti-Beta-Site APP Cleaving Enzyme 1 (bACE1)

Organism Species

Rattus norvegicus (Rat)
Source

Polyclonal antibody preparation
Purification

Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Buffer Formulation

PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Item Name

Beta-Site APP Cleaving Enzyme 1
Immunogen

RPA718Ra01-Recombinant Beta-Site APP Cleaving Enzyme 1 (bACE1)
Image number

2
Species reactivity

Rat
Sequence of immunogen

bACE1 (Gly181~Tyr366)
Aplication

WB,IHC
Clonality

Rabbit polyclonal
Concentration

500ug/ml
Alternative Names

ASP2; Beta Secretase; Memapsin 2; Aspartyl protease 2; Beta-site amyloid precursor protein cleaving enzyme 1; Membrane-associated aspartic protease 2
Applicable Secondary Antibody

SAA544Rb59, SAA544Rb58, SAA544Rb57, SAA544Rb18, SAA544Rb19
Manual link
Delivery condition

4℃ with ice bags
Storage instructions

Avoid repeated freeze/thaw cycles. Store at 4 ℃ for frequent use. Aliquot and store at -20℃ for 12 months.
Description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use. Enzymes are cleaving the substrate. If the substrate is DNA they are called restriction enzymes. Activating enzymes will cut off the domain that is biological active to become functional.

Gene target

100ug Beta-Site APP Cleaving bACE1
Gene symbol

APP-DT, APP, PABPC4, NAE1
Short name

100ug-Anti-Beta-Site APP Cleaving Enzyme 1 (bACE1)
Technique

Enzyme, anti-, anti, antibody to, antibodies, enzymes
Host

Rabbit
Alternative name

100ug-Antibody toBeta-Site amyloid beta (A4) precursor protein Cleaving Enzyme 1 (bACE1)
Alternative technique

enzymes, antibodies
Alternative to gene target

amyloid beta (A4) precursor protein, AAA and ABETA and ABPP and AD1 and APPI and CTFgamma and CVAP and PN-II and PN2, APP and IDBG-1100 and ENSG00000142192 and 351, growth factor receptor binding, nuclei, App and IDBG-172954 and ENSMUSG00000022892 and 11820, APP and IDBG-630293 and ENSBTAG00000017753 and 280722

Identity

HGNC:620
Gene

APP
Long gene name

amyloid beta precursor protein
Synonyms gene
- AD1
Synonyms gene name
- Alzheimer disease
- amyloid beta (A4) precursor protein
Synonyms
- alpha-sAPP
Synonyms name
- peptidase nexin-II
GenBank acession
- M15533
Locus

21q21.3
Discovery year

1986-01-01
Entrez gene record

351
Pubmed identfication
- 1679289
RefSeq identity
- NM_000484
Classification
- Receptor ligands
VEGA ID

OTTHUMG00000078438
Locus Specific Databases
- Alzheimer Disease & Frontotemporal Dementia Mutation Database

Identity

HGNC:8557
Gene

PABPC4
Long gene name

poly(A) binding protein cytoplasmic 4
Synonyms gene name
- poly(A)-binding protein, cytoplasmic 4 (inducible form)
- poly(A) binding protein, cytoplasmic 4 (inducible form)
Synonyms
- iPABP
- APP-1
Synonyms name
- activated-platelet protein 1
- Inducible poly(A)-binding protein
GenBank acession
- U33818
Locus

1p34.3
Discovery year

1999-12-17
Entrez gene record

8761
Pubmed identfication
- 10543404
RefSeq identity
- NM_001135653
Classification
- RNA binding motif containing
- Small nucleolar RNA protein coding host genes
VEGA ID

OTTHUMG00000009097

Name

Blotting, Western
Concept

Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data