GNF-5837

• Catalog number
  B1339-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  (Z)-1-(3-((3-((1H-pyrrol-2-yl)methylene)-2-oxoindolin-6-yl)amino)-4-methylphenyl)-3-(2-fluoro-5-(trifluoromethyl)phenyl)urea
• Description
  A potent and selective pan-TRK inhibitor, suppressing the activity of TrkA and TrkB with IC50 of 8 and 12 nM, respectively
• CAS Number
  1033769-28-6
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C28H21F4N5O2
• Molecular Weight
  535.49
• Cell Permeable
  Yes
• Purity
  >98% by HPLC
• Solubilities
  DMSO > 10 mM
• Handling
  Protect from air and light
• Tag Line
  A potent and selective pan-TRK inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• MDL Number
  MFCD24386809
• PubChem CID
  59397065
• PubChem CID Link
• SMILES
  CC1=C(C=C(C=C1)NC(=O)NC2=C(C=CC(=C2)C(F)(F)F)F)NC3=CC4=C(C=C3)C(=CC5=CC=CN5)C(=O)N4
• InChi
  1S/C28H21F4N5O2/c1-15-4-6-19(35-27(39)37-25-11-16(28(30,31)32)5-9-22(25)29)13-23(15)34-18-7-8-20-21(12-17-3-2-10-33-17)26(38)36-24(20)14-18/h2-14,33-34H,1H3,(H,36,38)(H2,35,37,39)/b21-12-
• InChi Key
  YYDUWLSETXNJJT-MTJSOVHGSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  GNF-5837  
• Short name
  GNF-5837
• Alternative name
  GNF-5837

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