Mouse BACE1 (Beta Site APP Cleaving Enzyme 1) CLIA Kit
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Catalog number
E-CL-M0134-96T
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Price
Please ask
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Size
96Test
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Detection Type
Colormetric
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Target Species
Mouse
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Target Synonym
ASP2, HSPC104, Beta Secretase 1, Memapsin 2, membrane-associated aspartic protease 2, aspartyl protease 2
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Test principle
This CLIA kit uses the Sandwich- CLIA principle. The micro CLIA plate provided in this kit has been pre-coated with an antibody specific to Mouse BACE1 . Standards or samples are added to the micro CLIA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for Mouse BACE1 and Avidin-Horseradish Peroxidase (HRP) conjugate are added successively to each micro plate well and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Mouse BACE1 , biotinylated detection antibody and Avidin-HRP conjugate will appear fluorescence. The Relative light unit (RLU) value is measured by the Chemiluminescence immunoassay analyzer. The RLU value is positively associated with the concentration of Mouse BACE1 . You can calculate the concentration of Mouse BACE1 in the samples by comparing the RLU value of the samples to the standard curve.
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Sensitivity
18.75pg/mL
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Detection Range
31.25~2000pg/mL
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Target Name
BACE1
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UNIProt ID
NA
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Tested Sample Types
Serum, Plasma, Cell supernatant
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Product Name
Mouse BACE1 (Beta Site APP Cleaving Enzyme 1) CLIA Kit
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Type
Sandwich
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Description
Enzymes are cleaving the substrate. If the substrate is DNA they are called restriction enzymes. Activating enzymes will cut off the domain that is biological active to become functional.
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Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin name
Mus musculus
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Gene target
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Gene symbol
APP-DT, BACE1, BACE1-AS, APP, PABPC4, NAE1
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Short name
Mouse BACE1 (Beta Site APP Cleaving Enzyme 1) CLIA Kit
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Technique
Enzyme, Mouse, enzymes, mouses
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Host
mouse
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Species
Mouse, Mouses
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Alternative name
Mouse BACE1 (b Site amyloid beta (A4) precursor protein Cleaving Enzyme 1) CLIA reagent
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Alternative technique
enzymes, murine, kits
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Alternative to gene target
amyloid beta (A4) precursor protein, AAA and ABETA and ABPP and AD1 and APPI and CTFgamma and CVAP and PN-II and PN2, APP and IDBG-1100 and ENSG00000142192 and 351, growth factor receptor binding, nuclei, App and IDBG-172954 and ENSMUSG00000022892 and 11820, APP and IDBG-630293 and ENSBTAG00000017753 and 280722
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Gene info
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Identity
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Gene
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Long gene name
APP divergent transcript
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Locus
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Discovery year
2020-06-12
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Classification
Gene info
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Identity
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Gene
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Long gene name
beta-secretase 1
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Synonyms gene
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Synonyms gene name
- beta-site APP-cleaving enzyme
- beta-site APP-cleaving enzyme 1
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GenBank acession
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Locus
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Discovery year
1999-10-29
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Entrez gene record
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Pubmed identfication
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
BACE1 antisense RNA
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Synonyms gene
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Synonyms gene name
- BACE1 antisense RNA (non-protein coding)
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Synonyms
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Synonyms name
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Locus
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Discovery year
2009-07-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
Gene info
Gene info
Product images
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