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IL-1 beta rat recombinant

IL-1 beta rat recombinant is available 3 times from Biovision labs

4130-1000 | IL-1 beta, rat recombinant size: 1 mg | 7,744.08 USD

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4130-10 | IL-1 beta, rat recombinant size: 10 ug | 348.46 USD

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4130-50 | IL-1 beta, rat recombinant size: 50 ug | 940.34 USD

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Synonyms Catabolin, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF)
Alternative_names Catabolin, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF)
Description An important mediator of inflammatory responses
Recombinant Yes
Source E. coli
Purity by SDS-PAGE ≥98%
Assay SDS-PAGE
Purity ≥98%
Biological activity The ED₅₀ as determined by the dose-dependent stimulation of murine D10S cells is 1 x 10⁷ units/mg.
Molecular Weight 17.3 kDa
Storage Temp. -20°C
Shipping Gel pack
Shelf Life 12 months
Appearance Lyophilized protein
Physical form description Sterile filtered and then lyophilized from 10 mM Sodium Acetate, pH 6.5
Reconstitution Instructions Centrifuge the vial prior to opening. Reconstitute in H₂O to a concentration of 0.1-1.0 mg/ml. The solution can then be diluted into other aqueous buffers and stored at +4°C for 1 week or –20°C for future use.
Background Information IL-1β is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1α and IL-1β binds to the same receptor and has similar biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, B-cell maturation and proliferation, mitogenic FGF-like activity and stimulation of the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1β is a secreted cytokine, IL-1α is predominantly a cell-associated cytokine. Recombinant rat IL-1β is a 17.4 kDa protein containing 153 amino acid residues.
Handling Centrifuge the vial prior to opening.
Usage For Research Use Only! Not to be used in humans
Gene The Interleukin-1 family (IL-1 family) is a group of 11 cytokines, which plays a central role in the regulation of immune and inflammatory responses to infections or sterile insults. Rec. E. coli interleukin-1 for cell culture or antibody production.
About Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
Latin name Rattus norvegicus
Additional source Recombinants or rec. proteins
Group recombinants
Gene targetIL-1 beta
Short name IL-1 beta, recombinant
Technique Recombinant
Host Rat
Species Rat
Alternative name Interleukin-1 b, rat recombinant
Alternative technique rec
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