Angiotensin I Converting Enzyme Activity (ACE1) Assay Kit (Fluorometric)
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Catalog number
K227-100
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Price
Please ask
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Size
100 assays
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Description
Industry's first kit to detect ACE1 activity in biological samples
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Summary
• Detection method - Fluorescence (Ex/Em = 330/430 nm) • Applications- Detection of ACE1 activity in tissue/cell lysates
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Detection Method
Fluorometric (Ex/Em = 330/430 nm)
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Species Reactivity
Mammalian
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Applications
Detection of ACE1 activity in tissue/cell lysates
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Sample Type
• Mammalian tissues: lung, heart, kidney • Serum, plasma
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Features Benefits
• Simple one-step reaction • Takes only 1-2 hrs • Non-radiometric fluorescent detection • HTP adaptable
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Storage Conditions
-20°C
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Shipping Conditions
gel pack
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Shelf life
12 months
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Background
Angiotensin I converting enzyme (ACE1, EC: 3.4.15.1), a dipeptidyl carboxypeptidase, is part of the renin-angiotensin system (RAS) that controls regulation of blood pressure by cleaving the C-terminal dipeptides of angiotensin I and bradykinin. It is found on the luminal surface of vascular endothelial cells, especially in pulmonary tissues. Elevated levels of ACE1 are found in patients suffering from sarcoidosis, leprosy, hyperthyroidism, acute hepatitis, primary biliary cirrhosis, diabetes mellitus, multiple myeloma, osteoarthritis, amyloidosis, Gaucher’s disease, pneumoconiosis, histoplasmosis and miliary tuberculosis. BioVision’s ACE1 Activity Assay Kit utilizes an active ACE1 to cleave a synthetic o-aminobenzoyl peptide (Abz-based peptide) substrate to release a fluorophore. The released Abz can be easily quantified using a fluorescence microplate reader. This assay kit is simple, rapid and can detect ACE activity as low as 10 mU in biological samples
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Test
Biovision supplies other types of Assays as 1.
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Additional description
Enzymes are cleaving the substrate. If the substrate is DNA they are called restriction enzymes. Activating enzymes will cut off the domain that is biological active to become functional.
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Gene target
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Gene symbol
ACE
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Short name
Angiotensin I Converting Enzyme Activity (ACE1) Assay Kit (Fluorometric)
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Technique
Enzyme, Assay, assays, enzymes
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Host
Assay
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Alternative name
Angiotensin I Converting Enzyme Activity (ACE1) test reagent (fluorescence)
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Alternative technique
enzymes, arrays, kits
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Alternative to gene target
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, C-Kit and CD117 and PBT and SCFR, KIT and IDBG-18980 and ENSG00000157404 and 3815, transferase activity, Extracellular, Kit and IDBG-172083 and ENSMUSG00000005672 and 16590, KIT and IDBG-642326 and ENSBTAG00000002699 and 280832
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Gene info
Product images
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