Sphingosine 1 Phosphate Receptor 1 (EDG-1), Membrane Preparation

Host Source

NA
Clone Name

NA
Product Category

Drug Discovery
Species Reactivity

N/A
Application

[35S]GTPgS Labeling
Immunogen

NA
Purification Method

NA
Shipping Conditions

Ship on dry ice, freeze upon arrival
Storage conditions

Sphingosine 1 Phosphate Receptor 1 (EDG-1), Membrane Preparation should be stored at -70ºC. Aliquot to avoid freeze/thaw cycles
Datasheet link
Description

Associated membrane protein types are lipopolysaccharide selective barriers. Biological membranes include cell membranes, outer coverings of cells or organelles that allow passage of certain proteins and nuclear membranes, which cover a cell nucleus; and tissue membranes, such as mucosae and serosae. , The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

Gene target

Sphingosine Phosphate Receptor EDG-1 Membrane Preparation
Gene symbol

S1PR1, HEXIM1, S1PR5, LPAR2, LPAR1, BUD31, S1PR3, LPAR3, IGHVII-1-1, MIR1-1
Short name

Sphingosine 1 Phosphate Receptor 1 (EDG-1), Preparation
Isotype

NA
Alternative name

Sphingosine 1 Phosphate Receptor 1 (EDG-1), Membrane Preparation

Identity

HGNC:3165
Gene

S1PR1
Long gene name

sphingosine-1-phosphate receptor 1
Synonyms gene
- EDG1
Synonyms gene name
- endothelial differentiation, sphingolipid G-protein-coupled receptor, 1
Synonyms
- edg-1
- D1S3362
- CD363
GenBank acession
- M31210
Locus

1p21.2
Discovery year

1998-05-15
Entrez gene record

1901
Pubmed identfication
- 2160972
- 9488656
RefSeq identity
- NM_001400
Classification
- CD molecules
- Sphingosine 1-phosphate receptors
VEGA ID

OTTHUMG00000010835

Identity

HGNC:14299
Gene

S1PR5
Long gene name

sphingosine-1-phosphate receptor 5
Synonyms gene
- EDG8
Synonyms gene name
- endothelial differentiation, sphingolipid G-protein-coupled receptor, 8
Synonyms
- Edg-8
GenBank acession
- AK074661
Locus

19p13.2
Discovery year

2001-01-02
Entrez gene record

53637
Pubmed identfication
- 10799507
RefSeq identity
- NM_030760
Classification
- Sphingosine 1-phosphate receptors
VEGA ID

OTTHUMG00000180581

Identity

HGNC:3168
Gene

LPAR2
Long gene name

lysophosphatidic acid receptor 2
Synonyms gene
- EDG4
Synonyms gene name
- endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 4
Synonyms
- EDG-4
- LPA2
GenBank acession
- AF011466
Locus

19p13.11
Discovery year

1999-02-15
Entrez gene record

9170
Pubmed identfication
- 9525886
- 9804623
RefSeq identity
- NM_004720
Classification
- Lysophosphatidic acid receptors
VEGA ID

OTTHUMG00000182328

Identity

HGNC:3166
Gene

LPAR1
Long gene name

lysophosphatidic acid receptor 1
Synonyms gene
- EDG2
Synonyms gene name
- endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 2
Synonyms
- edg-2
- rec.1.3
- vzg-1
- Gpcr26
- Mrec1.3
- LPA1
GenBank acession
- U80811
Locus

9q31.3
Discovery year

1998-05-15
Entrez gene record

1902
Pubmed identfication
- 8922387
- 9070858
RefSeq identity
- NM_057159
Classification
- Lysophosphatidic acid receptors
VEGA ID

OTTHUMG00000020486

Identity

HGNC:29629
Gene

BUD31
Long gene name

BUD31 homolog
Synonyms gene
- G10
Synonyms gene name
- G10 maternal transcript homolog (Xenopus laevis)
- BUD31 homolog (yeast)
- BUD31 homolog (S. cerevisiae)
Synonyms
- YCR063W
- EDG-2
- EDG2
- fSAP17
- Cwc14
Synonyms name
- functional spliceosome-associated protein 17
GenBank acession
- BC022821
Locus

7q22.1
Discovery year

2006-03-10
Entrez gene record

8896
Pubmed identfication
- 7841202
RefSeq identity
- NM_003910
Classification
- Spliceosomal C complex
- NTC associated proteins
- Spliceosomal B complex
- Spliceosomal Bact complex
- Spliceosomal P complex
VEGA ID

OTTHUMG00000154602

Identity

HGNC:3167
Gene

S1PR3
Long gene name

sphingosine-1-phosphate receptor 3
Synonyms gene
- EDG3
- C9orf47
- C9orf108
Synonyms gene name
- endothelial differentiation, sphingolipid G-protein-coupled receptor, 3
- chromosome 9 open reading frame 47
- chromosome 9 open reading frame 108
Synonyms
Synonyms name
- sphingosine-1-phosphate receptor 3
GenBank acession
- AF022139
Locus

9q22.1
Discovery year

1998-05-15
Entrez gene record

1903
Pubmed identfication
- 8878560
- 9409733
RefSeq identity
- NM_005226
Classification
- Sphingosine 1-phosphate receptors
VEGA ID

OTTHUMG00000020173

Identity

HGNC:14298
Gene

LPAR3
Long gene name

lysophosphatidic acid receptor 3
Synonyms gene
- EDG7
Synonyms gene name
- endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 7
Synonyms
- LP-A3
- Edg-7
- RP4-678I3
- HOFNH30
- LPA3
GenBank acession
- AF127138
Locus

1p22.3
Discovery year

2001-01-02
Entrez gene record

23566
Pubmed identfication
- 10488122
RefSeq identity
- NM_012152
Classification
- Lysophosphatidic acid receptors
VEGA ID

OTTHUMG00000009925

Identity

HGNC:5670
Gene

IGHVII-1-1
Long gene name

immunoglobulin heavy variable (II)-1-1 (pseudogene)
Synonyms gene name
- immunoglobulin heavy variable (II)-1-1
- immunoglobulin heavy variable (II)-1-1 pseudogene
Synonyms
- IGHV(II)-1-1
GenBank acession
- AB019441
Locus

14q32.33
Discovery year

2000-04-17
Entrez gene record

28377
RefSeq identity
- NG_001019
Classification
- Immunoglobulin heavy locus at 14q32.33
VEGA ID

OTTHUMG00000152325