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Recombinant Mouse FcERI FCER1A Protein Fc tag

Recombinant Mouse FcERI FCER1A Protein Fc tag is available 2 times from Elabscience labs

PKSM040429-50µg | Recombinant Mouse FcERI / FCER1A Protein (Fc tag) size: 50µg | 504.61 USD

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PKSM040429-100µg | Recombinant Mouse FcERI / FCER1A Protein (Fc tag) 100µg size: 100µg | 750.32 USD

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Synonym Fce1a;fcepsilonri;FcERI;Fcr-5
Activity NA
Sequence Met1-Gln204
Fusion tag C-Fc
Accession P20489
Expressed Host HEK293 Cells
Shipping In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Purity > 85 % as determined by SDS-PAGE
Endotoxin< 1.0 EU per μg of the protein as determined by the LAL method
Stability and Storage Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Mol Mass 48 kDa
AP Mol Mass 63 kDa
Formulation Lyophilized from sterile PBS, pH 7.4
Background FcERI, also known as FCER1A, is the alpha subunit of the immunoglobulin epsilon receptor (IgE receptor). IgE receptor is a high affinity IgE receptor which plays a central role in allergic disease, coupling allergen and mast cell to initiate the inflammatory and immediate hypersensitivity responses that are characteristic of disorders such as hay fever and asthma. The allergic response occurs when 2 or more IgE receptors are crosslinked via IgE molecules that in turn are bound to an allergen (antigen) molecule. A perturbation occurs that brings about the release of histamine and proteases from the granules in the cytoplasm of the mast cell and leads to the synthesis of prostaglandins and leukotrienes--potent effectors of the hypersensitivity response. IgE receptor is comprised of an alpha subunit(FcERI), a beta subunit, and two gamma subunits. FcERI is glycosylated and contains 2 Ig-like (immunoglobulin-like) domains.
Test Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Latin name Mus musculus
Source Recombinants or rec. proteins
Group recombinants
Technique Recombinant, Mouse, FC
Host mouse
Label Fc Tag
Species Mouse
Alternative technique rec
Alternative to gene target Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide, FCE1A and FcERI, FCER1A and IDBG-103887 and ENSG00000179639 and 2205, IgE binding, Cell surfaces, Fcer1a and IDBG-205782 and ENSMUSG00000005339 and 14125, FCER1A and IDBG-630768 and ENSBTAG00000012887 and 506783
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