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Prolactin Receptor recombinant

Prolactin Receptor recombinant is available 5 times from Biovision labs

4989-20 | Prolactin Receptor, human recombinant size: 20 ug | 321.42 USD

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4989-1000 | Prolactin Receptor, human recombinant size: 1 mg | 6,736.93 USD

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4991-1000 | Prolactin Receptor, rat recombinant size: 1 mg | 5,554.67 USD

Catalog number 4991-1000
Supplier Biovision
Price 5,554.67 USD
Size 1 mg
Synonyms PRL-R, Prolactin receptor, Lactogen receptor, Prlr, PRL, luteotropic hormone, LTH, PRLR, PRL-R, PRL R
Alternative_names PRL-R, Prolactin receptor, Lactogen receptor, Prlr, PRL, luteotropic hormone, LTH, PRLR, PRL-R, PRL R
Biological activity Determined by the dose-dependent inhibition of Prolactin stimulated proliferation of Nb2 cells and by high affinity binding of ovine Prolactin and other lactogenic hormones.
Molecular Weight 24.12 kDa
Shipping Blue ice
Physical form description Sterile filtered and lyophilized from a concentrated (1 mg/ml) solution with 0.0045 mM NaHCO₃
Reconstitution Instructions Reconstitute in sterile dH₂O to a concentration of 0.1 -1 mg/ml and let the lyophilized pellet dissolve completely. This solution can then be diluted into other aqueous buffers
Background Information Prolactin is a pituitary hormone that plays a role in the stimulation of milk production, salt and H₂O regulation, growth, development and reproduction. The primary step in its action is the binding to a specific membrane receptor (prolactin receptor) which belongs to the superfamily of class 1 cytokine receptors. Prolactin is a hormone involved in a range of significant functions including ion transport and osmoregulation, stimulation of milk, protein synthesis as well as the regulation of numerous reproductive functions. Prolactin exerts its influence on different cell types through a signal transduction pathway which begins with the binding of the hormone to a transmembrane Prolactin receptor. PRLR varies in size (short and long forms) with tissue source and species, from ~40 kDa to 100 kDa. Recombinant human Prolactin Receptor (Extra Cellular Domain) produced in E.Coli is a non-glycosylated, Polypeptide chain containing 206 amino acids and having a molecular mass of 24.12 kDa.
About Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
Latin name Rattus norvegicus
Additional description The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
Additional source Recombinants or rec. proteins
Group recombinants
Host Rat
Species Rat
Alternative name Prolactin Receptor, rat recombinant
1. Gene info
Identity 9446
Gene PRLR
Long gene name prolactin receptor
Locus 5p13.2
Discovery year 1989-12-01
Entrez gene record 5618
Havana BLAST/BLAT OTTHUMG00000090789
Product images
    #Rat#.png#0#.jpegProlactin Receptor, rat recombinant

4991-50 | Prolactin Receptor, rat recombinant size: 50 ug | 472.10 USD

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4991-10 | Prolactin Receptor, rat recombinant size: 10 ug | 234.49 USD

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Description A cytokine receptor
Recombinant Yes
Source E. coli
Purity by SDS-PAGE ≥97%
Assay SDS-PAGE
Purity ≥97%
Storage Temp. -20°C
Shelf Life 12 months
Appearance Lyophilized protein
Handling Centrifuge the vial prior to opening.
Usage For Research Use Only! Not to be used in humans
Gene targetProlactin Receptor
Short name Prolactin Receptor, recombinant
Technique Recombinant
Alternative technique rec
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