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GNF 7 for cell activation

GNF 7 for cell activation is available 2 times from Biovision labs

B1139-5 | GNF-7 for cell activation size: 5 mg | 248.93 USD

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B1139-25 | GNF-7 for cell activation size: 25 mg | 807.84 USD

Catalog number B1139-25
Supplier Biovision
Price 807.84 USD
Size 25 mg
1. Gene info
Identity 34284
Gene RNU6-7
Long gene name RNA, U6 small nuclear 7
Synonyms
  • U6-7
Locus 14q12
Discovery year 2008-06-10
Entrez gene record 101954275
Pubmed identfication
  • 12711679
RefSeq identity
  • NR_104084
Classification
  • Small nuclear RNAs
Product images
    GNF-7
Description GNF-7 is a multi-targeted kinase inhibitor that inhibits activated CDC42 kinase 1 (ACK1) and germinal center kinase (GCK) inducing cell cycle arrest and apoptosis in leukemia cells harboring NRAS mutations. It also displays significant in vivo efficacy against T315l-Bcr-Abl without notable toxicity in a bioluminescent xenograft mouse model using transformed T315l-Bcr-Abl-Ba/F3 cell line that has a stable luciferase expression.
Peptide sequence N/A
CAS number 839706-07-9
Molecular weight 547.53
Category Biochemicals
Other name N-[3-[1,4-Dihydro-1-methyl-7-[(6-methyl-3-pyridinyl)amino]-2-oxopyrimido[4,5-d]pyrimidin-3(2H)-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide
Molecular formula C₂₈H₂₄F₃N₇O₂
Physical appearance White Solid
Supplied with N/A
Is this a salt? No
Is it cell-permeable? Yes
Purification ≥98% by HPLC
Reconstitute instructions DMSO (>30 mg/ml)
Storage condition -20°C
Shipping condition gel pack
Maximum time for storage 36 months
Storage instructions Protect from air and light
Additional description For cells, cell lines and tissues in culture till half confluency.
Gene targetGNF-7 for activation
Short name GNF-7 for activation
Technique activation
Alternative name GNF-7 to measure cellular activation
Tissue cell
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GNF-7 for activation | Technique alternative | 01012201616
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