Rabbit Anti-rat IL8 polyclonal antibody[IL8]
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Catalog numberMBS286076
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Price:
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Size1 mg
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Products_typeAntibody
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Products_gene_name[IL8]
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by MyBioSource they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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GeneInterleukin 8 (IL8 or chemokine (C-X-C motif) ligand 8, CXCL8) is a chemokine produced by macrophages and other cell types such as epithelial cells, airway smooth muscle cells and endothelial cells. Endothelial cells store IL-8 in their storage vesicles, the Weibel-Palade bodies. In humans, the interleukin-8 proteins encoded by the IL8 gene. IL-8 is initially produced as a precursor peptide of 99 amino acids long which then undergoes cleavage to create several active IL-8 isoforms. In culture, a 72 amino acid peptide is the major form secreted by macrophages. Recombinant, rec. E. coli interleukin-8 for cell culture or antibody production.
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GroupPolyclonals and antibodies
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AboutPolyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera. Rabbits are used for polyclonal antibody production by MyBioSource. Rabbit antibodies are very stable and can be stored for several days at room temperature. MyBioSource adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long. Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
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Latin nameOryctolagus cuniculus, Rattus norvegicus
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French translationanticorps
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Gene target
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Gene symbolCXCL8
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Short nameRabbit Anti- IL8 polyclonal antibody[IL8]
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TechniquePolyclonal, Antibody, Rabbit, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
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HostRabbit, Rabbits
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SpeciesRat, Rats
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Alternative nameproduction species: rabbit Antibody torat interleukin 8 polyclonal (antibody to-)[interleukin 8]
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Alternative techniquepolyclonals, antibodies, rabbit-anti
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Alternative to gene targetinterleukin 8, GCP-1 and GCP1 and IL8 and LECT and LUCT and LYNAP and MDNCF and MONAP and NAF and NAP-1 and NAP1, IL8 and IDBG-23954 and ENSG00000169429 and 3576, chemokine activity, Extracellular, IL8 and IDBG-643010 and ENSBTAG00000019716 and 280828
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Gene info
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Identity
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Gene
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Long gene nameC-X-C motif chemokine ligand 8
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Synonyms gene
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Synonyms gene name
- interleukin 8
- chemokine (C-X-C motif) ligand 8
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Synonyms
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Synonyms name
- neutrophil-activating peptide 1
- granulocyte chemotactic protein 1
- monocyte-derived neutrophil chemotactic factor
- lung giant cell carcinoma-derived chemotactic protein
- tumor necrosis factor-induced gene 1
- monocyte-derived neutrophil-activating peptide
- lymphocyte derived neutrophil activating peptide
- beta endothelial cell-derived neutrophil activating peptide
- alveolar macrophage chemotactic factor I
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GenBank acession
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Locus
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Discovery year1989-06-30
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Chemokine ligands
- Interleukins
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data