CASP10, CT (Caspase-10, CASP-10, ICE-like Apoptotic Protease 4, Apoptotic Protease Mch-4, FAS-associated Death Domain Protein Interleukin-1B-converting Enzyme 2, FLICE2, Caspase-10 Subunit p23/17, Caspase-10 Subunit p12, MCH4)
-
Catalog number
GEN648344
-
Price
Please ask
-
Size
100ug
-
-
Also known as
CASP10
-
Other names
caspase-10 isoform 5 preproprotein; Caspase-10; caspase-10; CASP-10; FADD-like ICE2; apoptotic protease MCH-4; ICE-like apoptotic protease 4; interleukin-1B-converting enzyme 2; caspase 10, apoptosis-related cysteine protease; FAS-associated death domain protein interleukin-1B-converting enzyme 2; caspase 10, apoptosis-related cysteine peptidase; Apoptotic protease Mch-4; FAS-associated death domain protein interleukin-1B-converting enzyme 2; FLICE2; ICE-like apoptotic protease 4
-
Category
Antibodies
-
Subcategory
Mnoclonal antibodies
-
Gene name
CASP10; CASP10; MCH4; ALPS2; FLICE2; MCH4; CASP-10; FLICE2
-
Gene name synonims
CASP10; CASP10; MCH4; ALPS2; FLICE2; MCH4; CASP-10; FLICE2
-
Other gene names
CASP10; CASP10; MCH4; ALPS2; FLICE2; MCH4; CASP-10; FLICE2
-
Clonality
Monoclonal
-
Immunoglobulin isotype
IgG2a
-
Clone
N/A
-
Host organism
Rat (Rattus norvegicus)
-
Species reactivity
Human (Homo sapiens), Mouse (Mus musculus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
-
Specificity and cross reactivity
Recognizes human Caspase-10. Species Crossreactivity: mouse.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
-
Purification method
Affinity Purified by immunoaffinity chromatography.
-
Form Appearance
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
-
Concentration
N/A
-
Storage and shipping
Store the antibody at +4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
-
Tested applications
Western Blot (WB)
-
Description
Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways. Enzymes are cleaving the substrate. If the substrate is DNA they are called restriction enzymes. Activating enzymes will cut off the domain that is biological active to become functional.
-
Gene target
-
Gene symbol
CASP10, FAS-AS1, CASP1, FASN, IGHD1OR15-1B, XCL2, CASP5, CES2, CARD18, CASP9
-
Short name
CASP10, CT (Caspase-10, CASP-10, ICE-like Apoptotic Protease 4, Apoptotic Protease Mch-4, FAS-associated Death Domain Protein Interleukin-1B-converting Enzyme 2, FLICE2, Caspase-10 Subunit p23/17, Caspase-10 Subunit p12, MCH4)
-
Technique
Enzyme, enzymes
-
Alternative name
Anti-CASP10, CT (Caspase-10, CASP-10, ICE-like Apoptotic Protease 4, Apoptotic Protease Mch-4, FAS-associated Death Domain Protein Interleukin-1B-converting Enzyme 2, FLICE2, Caspase-10 Subunit p23/17, Caspase-10 Subunit p12, MCH4)
-
Alternative technique
enzymes
-
Alternative to gene target
caspase 10, apoptosis-related cysteine peptidase, ALPS2 and FLICE2 and MCH4, CASP10 and IDBG-78470 and ENSG00000003400 and 843, cysteine-type endopeptidase activity involved in apoptotic signaling pathway, Plasma membranes
-
Gene info
-
Identity
-
Gene
-
Long gene name
caspase 10
-
Synonyms gene name
- caspase 10, apoptosis-related cysteine protease
- caspase 10, apoptosis-related cysteine peptidase
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year
1997-04-21
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Caspases
- Death effector domain containing
- Death inducing signaling complex
-
VEGA ID
-
Locus Specific Databases
Gene info
-
Identity
-
Gene
-
Long gene name
FAS antisense RNA 1
-
Synonyms gene
-
Synonyms gene name
- FAS antisense RNA (non-protein coding)
- FAS antisense RNA 1 (non-protein coding)
-
Synonyms
-
Locus
-
Discovery year
2009-07-16
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
Gene info
-
Identity
-
Gene
-
Long gene name
caspase 1
-
Synonyms gene
-
Synonyms gene name
- caspase 1, apoptosis-related cysteine protease (interleukin 1, beta, convertase)
- caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)
- caspase 1, apoptosis-related cysteine peptidase
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year
1992-05-07
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Caspases
- Caspase recruitment domain containing
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene name
fatty acid synthase
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year
1994-05-17
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Short chain dehydrogenase/reductase superfamily
- 7BS orphan methyltransferases
-
VEGA ID
Gene info
Gene info
Gene info
-
Identity
-
Gene
-
Long gene name
caspase 5
-
Synonyms gene name
- caspase 5, apoptosis-related cysteine protease
- caspase 5, apoptosis-related cysteine peptidase
-
Synonyms
-
Locus
-
Discovery year
1996-09-13
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Caspases
- Caspase recruitment domain containing
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene name
carboxylesterase 2
-
Synonyms gene name
- carboxylesterase 2 (intestine, liver)
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year
1993-09-30
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
-
VEGA ID
Gene info
Gene info
-
Identity
-
Gene
-
Long gene name
caspase 9
-
Synonyms gene name
- caspase 9, apoptosis-related cysteine protease
- caspase 9, apoptosis-related cysteine peptidase
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year
1996-11-11
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Caspases
- Apoptosome
- Caspase recruitment domain containing
- Protein phosphatase 1 regulatory subunits
-
VEGA ID
MeSH Data
-
Name
-
Concept
Scope note:
Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.
-
Tree numbers
Similar products