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GDF 15 D human recombinant

GDF 15 D human recombinant is available 3 times from Biovision labs

4570-100 | GDF-15-D, human recombinant size: 100 ug | 827.34 USD

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4570-20 | GDF-15-D, human recombinant size: 20 ug | 370.55 USD

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4570-1000 | GDF-15-D, human recombinant size: 1 mg | 6,866.51 USD

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Synonyms MIC1, PDF, PLAB, PTGFB
Alternative_names MIC-1, Placental TGFβ, Prostate differentiation factor
Description A protein with functions in regulating inflammatory and apoptotic pathways
Recombinant Yes
Source E. coli
Purity by SDS-PAGE ≥95%
Assay SDS-PAGE
Biological activity The activity is determined by the inhibition of DU-145 cells and is typically 1-2 µg/ml.
Results 1-2 µg/ml
Molecular Weight 26.8 kDa
Storage Temp. -20°C
Shipping Blue ice
Shelf Life 12 months
Appearance Lyophilized protein
Physical form description Sterile filtered and lyophilized with no additives
Reconstitution Instructions Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile 5 mM acetic acid at a concentration of 0.1 mg/ml, which can be further diluted into other aqueous solutions.
Background Information Growth and differentiation factor 15 (GDF-15) is a TGFβ family member, made by in the placenta and heart tissues, that has a role in regulating inflammatory and apoptotic pathways. GDF-15 has become an immerging marker of early heart disease and has the potential as being used as a molecule for screening patients for early heart failure. Recombinant human GDF-15 (D-variant) is a non-glycosylated, disulfide linked homodimer. It is comprised of two identical 120 amino acid monomers and has a total molecular mass of 26.8 kDa. There is a His to an Asp substitution at position 7.
Amino acid sequence MARNGDDCPL GPGRCCRLHT VRASLEDLGW ADWVLSPREV QVTMCIGACP SQFRAANMHA QIKTSLHRLK PDTVPAPCCV PASYNPMVLI QKTDTGVSLQ TYDDLLAKDC HCI
Handling Centrifuge the vial prior to opening.
Usage For Research Use Only! Not to be used in humans
Properties Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Additional source Recombinants or rec. proteins
Group recombinants
Gene targetGDF-15-D
Short name GDF-15-D, recombinant
Technique Recombinant
Species Human
Alternative name GDF-15-D, H. sapiens recombinant
Alternative technique rec
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