Function: Human Vasoactive Intestinal Peptide Receptor-1 (VIPR1) is a G-protein-coupled receptor for vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating polypeptide (PACAP). VIPR1 mediates suppression of chemotaxis and matrix metalloproteinase expression elicited by some cytokines and chemokines. Although structurally-related to a second receptor for VIP (VIPR2), there are differences in the expression and function of VIPR1 and VIPR2. VIPR1 on tumor cells mediates tumor cell migration induced by VIP._x000B__x000B_Cell Distribution: hVIPR1 is expressed on T cells, macrophages, mast cells, platelets, and non-immune cells. VIP receptors are found in the CD3 positive zone around lymphoid follicles. In the spleen, VIP receptors are detected in periarterial lymphatic sheaths. In the thymus, VIP receptors are present in cortex and medulla. VIP receptors are expressed in tumor metastasis and on human colonic adenocarcinoma cell lines, HT29, SW403, DLD-1 and Caco-2.
Antibody come from
Protein A/G Chromatography
Antigen-antibody binding interaction
Mouse anti VipR 1 (Vasoactive Intestinal PE Rec-1) Antibody
Antibody is raised in
Antibody's reacts with
Antibody's reacts with these species
This antibody doesn't cross react with other species
No Data Available
Western Blot, Flow Cytometry
Antibody's suited for
no information yet
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Mouse anti VipR 1 (Vasoactive Intestinal PE Rec-1)
Mouse antibody to VipR 1 (Vasoactive Intestinal peroxidase Rec-1)