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Anti-P53(wt-p53) (D2F7) Monoclonal, ALEXA Fluor 594

Anti-P53(wt-p53) (D2F7) Monoclonal, ALEXA Fluor 594 is available 1 time from Bioss monoclonal antibodies labs

GENTObsm-2346M-A594 | Anti-P53(wt-p53) (D2F7) Monoclonal, ALEXA Fluor 594 size: 100 microliters | 578.63 USD

Catalog number GENTObsm-2346M-A594
Price 578.63 USD
Size 100 microliters
1. Gene info
Identity 11998
Gene TP53
Long gene name tumor protein p53
Synonyms
  • p53
  • LFS1
Synonyms name
  • Li-Fraumeni syndrome
GenBank acession
  • AF307851
Locus 17p13.1
Discovery year 1986-01-01
Entrez gene record 7157
Pubmed identfication
  • 6396087
  • 3456488
  • 2047879
RefSeq identity
  • NM_000546
Havana BLAST/BLAT OTTHUMG00000162125
Locus Specific Databases
  • IARC TP53 Mutation Database
  • p53 UMD TP53 mutation database
  • Database of Germline p53 Mutations
  • MUTP53LOAD, Mutant p53 Loss Of Activity Database
  • LRG_321
Product images
    #anti-#.jpganti-#.jpgGENTObsm#.jpg
Type Conjugated Primary Antibody
Conjugated with ALEXA FLUOR 594
Host organism Mouse (Mus musculus)
Target Protein/Peptide P53wt-p53
Specificity Highly specific antibody against P53wt-p53
Modification Not modified
Clonality Monoclonal Antibodies
Clone D2F7
Concentration 1ug per 1ul
Antigen Source KLH conjugated synthetic peptide derived from human P53(wt-p53)
Gene ID 7157
Applications IF(IHC-P)
Applications with corresponding dilutions IF(IHC-P)(1:50-200)
Cross Reactive species Human (Homo sapiens), Rat (Rattus norvegicus)
Cross Reactive Species details No significant cross reactivity is observed
Background information This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013].
Purification method Purified by Protein G.
Storage Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Excitation emission 590nm/617nm
Synonyms Widespread p53; Wtp53; Antigen NY-CO-13; Cellular tumor antigen p53; Cys 51 Stop; HGNC11998; LFS1; p53; p53 Cellular Tumor Antigen; p53 Tumor Suppressor; Phosphoprotein p53; TP53; Transformation related protein 53; TRP53; Tumor protein p53; Tumour Protein p53; P53_HUMAN; TP53.
Alternative name 1 P53(wt-p53) (D2F7) Monoclonal Antibody, ALEXA FLUOR® 594 Conjugated
Alternative name 2 P53(wt-p53) (D2F7) Monoclonal anti-, ALEXA FLUOR 594 Conjugated
Advisory Cycles of freezing and thawing should be avoided as such cycles may denature the peptide chains of the antibody and reduce its affinity, specificity and reactivity. For antibodies in a liquid form or reconstituted lyophilized antibodies - small amounts of the soultion could be captured on the cap or the walls of the container. Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom.
Properties For facs or microscopy Alexa 1 conjugate.
Conjugation Alexa Fluor,ALEXA FLUOR® 594
Conjugated Alexa conjugate 1
Description This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
About Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
Gene targetP53(wt-p53 D2F7 Monoclonal
Short name Anti-P53(wt-p53) (D2F7) Monoclonal,
Technique anti
Isotype Immunoglobulin G (IgG)
Label ALEXA FLUOR 594
Alternative name antibody to-P53(wt-p53) (D2F7) monoclonal, ALEXA Fluor 594
Alternative technique antibodies
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