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Also known as
NAK / TBK1
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Other names
serine/threonine-protein kinase TBK1; Serine/threonine-protein kinase TBK1; serine/threonine-protein kinase TBK1; NF-kB-activating kinase; NF-kappa-B-activating kinase; TANK-binding kinase 1; NF-kappa-B-activating kinase; T2K; TANK-binding kinase 1
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Category
Antibodies
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Subcategory
Mnoclonal antibodies
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Gene name
NAK
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Gene name synonims
N/A
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Other gene names
TBK1; TBK1; NAK; T2K; NAK
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Clonality
Monoclonal
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Immunoglobulin isotype
IgG1,k
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Clone
108A429
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Host organism
Mouse (Mus musculus)
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Species reactivity
Gibbon, Bovine, Dog, Gorilla, Hamster, Horse, Human (Homo sapiens), Monkey, Mouse (Mus musculus), Pig, Rabbit (Oryctolagus cuniculus), Rat (Rattus norvegicus) Predicted Reactivity: Chicken (at least 90% immunogen sequence identity); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivity
A synthetic peptide corresponding to amino acids 563-577 YYQFKKDKAERRLAYC of human TBK1. GenBank no. NP-037386.1 was used as immunogen. This sequence is 100% conserved between human, mouse, rat, dog and cow.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification method
Protein G Purified
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Form Appearance
PBS, 0.05% BSA, 0.05% sodium azide. Sourced in TCS.
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Concentration
0.5 mg/ml
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Storage and shipping
For long term storage, keep the antibody at -20 degrees Celsius. Short term storage of the antibody can be done at +4 degrees Celsius. Cycles of freezing/defrosting can damage the peptide chains of the antibodies thus reducing the activity.
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Tested applications
Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
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Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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About
Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
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Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin name
Mus musculus
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French translation
anticorps
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Gene target
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Gene symbol
TBK1, NR4A1
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Short name
Mouse Monoclonal [clone 108A429] (IgG1 k) NAK / TBK1 Antibody
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Technique
Mouse monoclonal, Antibody, Mouse, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
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Host
mouse monoclonal, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
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Isotype
IgG1
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Species
Human, Humans, Mouses
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Alternative name
Anti-Mouse Monoclonal [clone 108A429] (IgG1,k) to Human NAK / TBK1
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Alternative technique
antibodies, murine
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Alternative to gene target
TANK-binding kinase 1, TBK1 and IDBG-44993 and ENSG00000183735 and 29110, transferase activity, Cytoplasm, Tbk1 and IDBG-192882 and ENSMUSG00000020115 and 56480, TBK1 and IDBG-634420 and ENSBTAG00000017401 and 533141
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Clone name
108A429
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