BACE, Asp2 (CT) (Memapsin2, Beta-site APP Cleaving Enzyme, Aspartyl Protease 2)
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Catalog numberMBS621619
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PricePlease ask
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Size100ul
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Alternative name1Anti-BACE, Asp2 (CT) (Memapsin2, Beta-site APP Cleaving Enzyme, Aspartyl Protease 2)
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Alternative name2BACE, Asp2 (CT) (Memapsin2, Beta-site APP Cleaving Enzyme, Aspartyl Protease 2)
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Alternative name3BACE, Asp2 (CT) (Memapsin2, Beta-site APP Cleaving Enzyme, Aspartyl Protease 2)
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Alternative name4BACE, Asp2
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Alternative name5Anti -BACE, Asp2 (CT) (Memapsin2, Beta-site APP Cleaving Enzyme, Aspartyl Protease 2)
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Other namesbeta-secretase 1 isoform D preproprotein; Beta-secretase 1; beta-secretase 1; asp 2; memapsin-2; APP beta-secretase; aspartyl protease 2; beta-site APP cleaving enzyme 1; beta-secretase 1 precursor variant 1; transmembrane aspartic proteinase Asp2; membrane-associated aspartic protease 2; beta-site amyloid beta A4 precursor protein-cleaving enzyme; beta-site APP-cleaving enzyme 1; Aspartyl protease 2; ASP2; Asp 2; Beta-site amyloid precursor protein cleaving enzyme 1; Beta-site APP cleaving enzyme 1; Memapsin-2; Membrane-associated aspartic protease 2
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Gene nameN/A
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Gene name synonimsN/A
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Other gene namesBACE1; BACE1; ASP2; BACE; HSPC104; BACE; KIAA1149; ASP2; Asp 2
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CategoryAntibodies
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ClonalityPolyclonal
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Immunoglobulin isotypeIgG
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ClonePolyclonal antibody
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Host organismHost: Goat; Source: Human
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Species reactivityHuman
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Specificity and cross reactivityRecognizes human beta amyloid cleaving enzyme (BACE), a 70kD aspartic protease. BACE is involved in the cleavage of the amyloid precursor protein (APP) to generate amyloid beta peptide. Cerebral deposition of amyloid beta peptide is an early feature of Alzheimer's disease.
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Purification methodSerum.
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Form AppearanceSerum. Supplied as a liquid with 0.1% sodium azide.
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ConcentrationN/A
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Storage and shippingStore productone at -20 degrees Celsius.
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Tested forImmunohistochemistry (IHC)
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Descriptionproductone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.
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AdvisoryIn order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
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Additional descriptionEnzymes are cleaving the substrate. If the substrate is DNA they are called restriction enzymes. Activating enzymes will cut off the domain that is biological active to become functional.
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Gene target
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Gene symbolAPP-DT, BACE1, APP, PABPC4, NAE1
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Short nameBACE, Asp2 (CT) (Memapsin2, Beta-site APP Cleaving Enzyme, Aspartyl Protease 2)
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TechniqueEnzyme, enzymes
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Alternative nameBACE, Asp2 (CT) (Memapsin2, b-site amyloid beta (A4) precursor protein Cleaving Enzyme, Aspartyl Protease 2)
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Alternative techniqueenzymes
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Alternative to gene targetamyloid beta (A4) precursor protein, AAA and ABETA and ABPP and AD1 and APPI and CTFgamma and CVAP and PN-II and PN2, APP and IDBG-1100 and ENSG00000142192 and 351, growth factor receptor binding, nuclei, App and IDBG-172954 and ENSMUSG00000022892 and 11820, APP and IDBG-630293 and ENSBTAG00000017753 and 280722
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Gene info
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Identity
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Gene
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Long gene nameAPP divergent transcript
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Locus
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Discovery year2020-06-12
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Classification
- Divergent transcripts
Gene info
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Identity
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Gene
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Long gene namebeta-secretase 1
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Synonyms gene
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Synonyms gene name
- beta-site APP-cleaving enzyme
- beta-site APP-cleaving enzyme 1
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GenBank acession
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Locus
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Discovery year1999-10-29
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Entrez gene record
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Pubmed identfication
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Classification
- Peptidase family A1
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameamyloid beta precursor protein
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Synonyms gene
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Synonyms gene name
- Alzheimer disease
- amyloid beta (A4) precursor protein
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1986-01-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Receptor ligands
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namepoly(A) binding protein cytoplasmic 4
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Synonyms gene name
- poly(A)-binding protein, cytoplasmic 4 (inducible form)
- poly(A) binding protein, cytoplasmic 4 (inducible form)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1999-12-17
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- RNA binding motif containing
- Small nucleolar RNA protein coding host genes
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameNEDD8 activating enzyme E1 subunit 1
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Synonyms gene
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Synonyms gene name
- amyloid beta precursor protein binding protein 1, 59kDa
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-01-13
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Ubiquitin like modifier activating enzymes
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VEGA ID
