Filters
Ajax processing
Ajax processing
Ajax processing
Ajax processing
Ajax processing
Ajax processing
Ajax processing
Ajax processing
Ajax processing

Neuregulin Heregulin 1β

Neuregulin Heregulin 1β is available 5 times from Biovision labs

4711-10 | Neuregulin/Heregulin-1β (NRG-1β/HRG-1β), human recombinant size: 10 ug | 159.15 USD

Loading

4711-1000 | Neuregulin/Heregulin-1β (NRG-1β/HRG-1β), human recombinant size: 1 mg | 3,306.05 USD

Loading

4711-50 | Neuregulin/Heregulin-1β (NRG-1β/HRG-1β), human recombinant size: 50 ug | 280.85 USD

Loading

6650-30T | Neuregulin/Heregulin-1β Antibody size: 30 μg | 162.87 USD

Loading

6650-100 | Neuregulin/Heregulin-1β Antibody size: 100 μg | 367.34 USD

Loading
Synonyms NGR beta 1, Heregulin, HRG 1beta, Neuregulin, Neuregulin1 (NRG1-β1), Neu differentiation factor, Pro-neuregulin-1, Acetylcholine receptor-inducing activity, Breast cancer cell differentiation factor p45, Glial growth factor, Heregulin, Neu differentiation factor, Sensory and motor neuron-derived factor
Alternative_names NGR beta 1, Heregulin, HRG 1beta, Neuregulin, Neuregulin1 (NRG1-β1), Neu differentiation factor, Pro-neuregulin-1, Acetylcholine receptor-inducing activity, Breast cancer cell differentiation factor p45, Glial growth factor, Heregulin, Neu differentiation factor, Sensory and motor neuron-derived factor
Recombinant Yes
Source E. coli
Purity by SDS-PAGE ≥98%
Assay SDS-PAGE
Purity ≥98%
Biological activity The ED₅₀ was determined by the dose-dependent stimulation of the proliferation of human MCF-7 cells is < 0.5 ng/ml, corresponding to a specific activity of > 2 x 10⁶ units/mg.
Molecular Weight 7.86 kDa
Storage Temp. -20°C
Shipping Gel pack
Shelf Life 12 months
Physical form description< 0.5 ng/ml
Reconstitution Instructions Reconstitute in H₂O to a concentration of 0.1-1.0 µg/µl. The solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.
Background Information Neuregulin/Heregulin is a family of structurally related polypeptide growth factors derived from alternatively spliced genes (NRG1, NRG2, NRG3 and NRG4). To date, there are over 14 soluble and transmembrane proteins derived from the NRG1 gene. Proteolytic processing of the extraCellular domain of the transmembrane NRG1 isoforms release soluble growth factors. HRG1-β1 contains an Ig domain and an EGF-like domain that is necessary for direct binding to receptor tyrosine kinases erb3 and erb4. This binding induces erb3 and erb4 heterodimerization with erb2, stimulating intrinsic kinase activity, which leads to tyrosine phosphorylation. Although HRG1-β1 biological effects is still unclear, it has been found to promote motility and invasiveness of breast cancer cells which may also involve up-regulation of expression and function of the autocrine motility-promoting factor (AMF). Recombinant human Heregulin-β1 (HRG1-β1) is a 7.5 kDa polypeptide consisting of only the EGF domain of heregulin-β1 (65 amino acid residues).
Antibody Target Heregulin 1 beta
Target Alternative Name NGR beta 1, Heregulin, HRG 1beta, Neuregulin
Antibody Type Polyclonal
Species Reactivities Human
Immunogen Sequence Recombinant protein Heregulin-1 beta (177-241 aa) (BV-M66)
Accession # Q15491
Gene Id 3084
Form Liquid
Formulation 0.5 mg/ml in PBS (pH 7.2) containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.03% proclin
Purification Affinity Purified Antibody
Application Western blot
Positive Control Western blot: Recombinant protein
Application And Usages Western blot: ~1:200
Storage Condition -20 °C
Shipping Condition gel pack
Western Blot Verified Verified
Immunocytochemistry Verified Not Verified
Immunofluorescence Verified Not Verified
Immunoprecipitation Verified Not Verified
ELISA Verified Not Verified
ChIP Verified Not Verified
Flow Cytometry Verified Not Verified
Similar products
Urotensin II NT UII Suppplier: MBS Polyclonals
Price: 716.85 USD
PPIAL4A siRNA (Human) Suppplier: MyBioSource
Price: 538.53 USD
26-30mm Medium Test Tube Rack,Adj. Angle & Height Suppplier: Genesee
Price: 531.39 USD
TBC1D13 Primary Antibody Suppplier: EnoGene
Price: 505.24 USD
Neuregulin/Heregulin-1B Suppplier: Gentaur Genprice
Price: 429.16 USD
PIC 303FA3SA (Panneau rigide en polypropylène - dos adhésif) Suppplier: Brady Benelux NL
Price: 301.96 USD
SIK3 Peptide Suppplier: Zyagen
Price: 242.52 USD
SLC39A3 Polyclonal Antibody Suppplier: MyBioSource
Price: 204.47 USD
3-Chloro-4-fluorobenzoic acid Suppplier: Molekula
Price: 168.81 USD
Dog Somatotropin ELISA Kit Suppplier: MyBioSource
Price: 5.94 USD
Cobicistat[Cobicistat] Suppplier: MyBioSource
Price: 5.94 USD
Mouse Emerin Emd Suppplier: MBS Recombinant
Price: 2 043.55 USD
Recombinant Bovine Replication Suppplier: MyBioSource
Price: 0.00 USD
5-Iodo-2-furaldehyde Suppplier: SFC
Price: 0.00 USD
Ask
Ajax processing
Close
Neuregulin Heregulin 1β - Gentaur.com
Filters
EU:+32-(0)1-658-90-45 US:+1-(408)780-0908 [email protected]
  • Neuregulin/Heregulin-1β
  • NRG-1β/HRG-1β
Back
Contact us
Ajax processing
Close
Chat with gentaur.com employee