PDGFRA, CT (E1063) (Alpha-type Platelet-derived Growth Factor Receptor, PDGF-R-alpha, CD140 Antigen-like Family Member A, CD140a Antigen, CD140a)

• Catalog number
  MBS627534
• Price
  Please ask
• Size
  0.2 mL

• Products_type
  Antibody
• Products_short_name
  [PDGFRA]
• Products_name_syn
  [Anti -PDGFRA, CT (E1063) (Alpha-type Platelet-derived Growth Factor Receptor, PDGF-R-alpha, CD140 Antigen-like Family Member A, CD140a Antigen, CD140a)]
• Other_names
  [PDGFRA protein; PDGFRA protein; alpha-type platelet-derived growth factor receptor; PDGF-R-alpha; CD140a antigen; PDGFRA/BCR fusion; OTTHUMP00000158882; OTTHUMP00000218656; CD140 antigen-like family member A; rearranged-in-hypereosinophilia-platelet derived growth factor receptor alpha fusion protein; platelet-derived growth factor receptor, alpha polypeptide]
• Other_gene_names
  [PDGFRA; PDGFRA; CD140A; PDGFR2; MGC74795; RHEPDGFRA]
• Clonality
  Polyclonal
• Reactivity
  Human, Mouse
• Specificity
  Recognizes human PDGFRA. Species Crossreactivity: mouse.
• Purity
  Affinity Purified Purified by Protein G affinity chromatography.
• Form
  Supplied as a liquid in PBS, 0.09% sodium azide.
• Storage_stability
  May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Tested_application
  ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Description
  The PDGFRA, CT (E1063) (Alpha- Platelet-derived Growth Factor Receptor, PDGF-R-alpha, CD140 Antigen-like Family Member A, CD140a Antigen, CD140a) is a α- or alpha protein sometimes glycoprotein present in blood. Antigens are peptides or recombinant or native dependent on the production method. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. Platelets, also called thrombocytes or cloth cells in blood and are needed to stop bleeding by clumping and clotting the blood the vessels when the an injury occurs. Teh bone marrow will produce the platelets that have no nucleus. Platelates are unique to mammals, the are curved shaped 1900nm to 3100 nm large nucleus free clothing structures. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  PDGFRA   E1063   Alpha   Platelet-derived   Growth   Factor   Receptor   PDGF-R-alpha   CD140   like   Family   Member   CD140a   CD140a  
• Gene symbol
  PDGFRA, PDGFA, RRAS, PDGFRB, DAD1P1, HNRNPR, CLDN4, MC1R, PTPRK, CTNNA2
• Short name
  PDGFRA, CT (E1063) (Alpha- Platelet-derived Growth Factor Receptor, PDGF-R-alpha, CD140 Antigen-like Family Member A, CD140a Antigen, CD140a)
• Technique
  antigen, antigenes
• Host
  Rabbit
• Isotype
  IgG
• Alternative name
  platelet-derived growth factor receptor, a polypeptide, CT (E1063) (a-classification Platelet-derived Growth Factor Receptor, PDGF-R-a, CD140 protein-like family Member A, CD140a protein, CD140a)
• Alternative technique
  antigenes
• Alternative to gene target
  platelet-derived growth factor receptor, alpha polypeptide, CD140A and PDGFR-2 and PDGFR2 and RHEPDGFRA, PDGFRA and IDBG-18854 and ENSG00000134853 and 5156, transferase activity, nuclei, Pdgfra and IDBG-171929 and ENSMUSG00000029231 and 18595, PDGFRA and IDBG-642308 and ENSBTAG00000007173 and 282301

Gene info

• Identity
  HGNC:8803
• Gene
  PDGFRA
• Long gene name
  platelet derived growth factor receptor alpha
• Synonyms gene name
  • platelet-derived growth factor receptor, alpha polypeptide
• Synonyms
  • CD140a
  • PDGFR2
  • GAS9
• GenBank acession
  • D50001
• Locus
  4q12
• Discovery year
  1989-05-19
• Entrez gene record
  5156
• Pubmed identfication
  • 8643452
• RefSeq identity
  • NM_006206
• Classification
  • I-set domain containing
  • Receptor tyrosine kinases
  • CD molecules
• VEGA ID
  OTTHUMG00000128699
• Locus Specific Databases
  • LRG_309

Gene info

• Identity
  HGNC:8799
• Gene
  PDGFA
• Long gene name
  platelet derived growth factor subunit A
• Synonyms gene name
  • platelet-derived growth factor alpha polypeptide
• Synonyms
  • PDGF1
  • PDGF-A
• Synonyms name
  • PDGF A-chain
  • platelet-derived growth factor alpha chain
• Locus
  7p22.3
• Discovery year
  1986-01-01
• Entrez gene record
  5154
• Pubmed identfication
  • 1505216
  • 2536956
• VEGA ID
  OTTHUMG00000151412

Gene info

• Identity
  HGNC:10447
• Gene
  RRAS
• Long gene name
  RAS related
• Synonyms gene name
  • related RAS viral (r-ras) oncogene homolog
• Synonyms
  • R-Ras
• Synonyms name
  • Oncogene RRAS
• Locus
  19q13.33
• Discovery year
  2001-06-22
• Entrez gene record
  6237
• Pubmed identfication
  • 3098437
• RefSeq identity
  • NM_006270
• Classification
  • RAS type GTPase family
• VEGA ID
  OTTHUMG00000183247

Gene info

• Identity
  HGNC:8804
• Gene
  PDGFRB
• Long gene name
  platelet derived growth factor receptor beta
• Synonyms gene
  • PDGFR
• Synonyms gene name
  • platelet-derived growth factor receptor, beta polypeptide
• Synonyms
  • JTK12
  • CD140b
  • PDGFR1
• GenBank acession
  • M21616
• Locus
  5q32
• Discovery year
  2001-06-22
• Entrez gene record
  5159
• RefSeq identity
  • NM_002609
• Classification
  • Receptor tyrosine kinases
  • CD molecules
  • I-set domain containing
• VEGA ID
  OTTHUMG00000130053

Gene info

• Identity
  HGNC:18295
• Gene
  DAD1P1
• Long gene name
  defender against cell death 1 pseudogene 1
• Synonyms gene
  • DAD1L
• Synonyms gene name
  • defender against cell death 1-like
• Synonyms
  • DAD-R
• Locus
  12p12.1
• Discovery year
  2007-07-26
• Entrez gene record
  56286
• Pubmed identfication
  • 10812081
  • 11912161
• RefSeq identity
  • NR_024064

Gene info

• Identity
  HGNC:5047
• Gene
  HNRNPR
• Long gene name
  heterogeneous nuclear ribonucleoprotein R
• Synonyms gene
  • HNRPR
• Synonyms
  • hnRNP-R
• GenBank acession
  • AF000364
• Locus
  1p36.12
• Discovery year
  1999-06-11
• Entrez gene record
  10236
• Pubmed identfication
  • 9421497
• RefSeq identity
  • NM_005826
• Classification
  • Heterogeneous nuclear ribonucleoproteins
  • RNA binding motif containing
• VEGA ID
  OTTHUMG00000003224

Gene info

• Identity
  HGNC:2046
• Gene
  CLDN4
• Long gene name
  claudin 4
• Synonyms gene
  • CPETR
  • CPETR1
• Synonyms
  • CPE-R
  • WBSCR8
  • hCPE-R
• Synonyms name
  • Clostridium perfringens enterotoxin receptor 1
  • Williams-Beuren syndrome chromosomal region 8 protein
• GenBank acession
  • AB000712
• Locus
  7q11.23
• Discovery year
  1998-04-22
• Entrez gene record
  1364
• Pubmed identfication
  • 9334247
  • 9892664
• RefSeq identity
  • NM_001305
• Classification
  • Claudins
• VEGA ID
  OTTHUMG00000023425

Gene info

• Identity
  HGNC:6929
• Gene
  MC1R
• Long gene name
  melanocortin 1 receptor
• Synonyms gene name
  • melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
• Synonyms
  • MSH-R
• Synonyms name
  • alpha melanocyte stimulating hormone receptor
• Locus
  16q24.3
• Discovery year
  1993-07-27
• Entrez gene record
  4157
• Pubmed identfication
  • 8458079
• RefSeq identity
  • NM_002386
• Classification
  • Melanocortin receptors
• VEGA ID
  OTTHUMG00000171163

Gene info

• Identity
  HGNC:9674
• Gene
  PTPRK
• Long gene name
  protein tyrosine phosphatase receptor type K
• Synonyms
  • R-PTP-kappa
• GenBank acession
  • L77886
• Locus
  6q22.33
• Discovery year
  1998-02-09
• Entrez gene record
  5796
• Pubmed identfication
  • 9047348
  • 8663237
• Classification
  • Protein tyrosine phosphatases receptor type
  • Fibronectin type III domain containing
  • Immunoglobulin like domain containing
• VEGA ID
  OTTHUMG00000015536

Gene info

• Identity
  HGNC:2510
• Gene
  CTNNA2
• Long gene name
  catenin alpha 2
• Synonyms gene name
  • catenin (cadherin-associated protein), alpha 2
• Synonyms
  • CAP-R
  • CT114
• Synonyms name
  • cadherin-associated protein, related
  • cancer/testis antigen 114
  • alpha-N-catenin
• Locus
  2p12
• Discovery year
  1993-07-13
• Entrez gene record
  1496
• Pubmed identfication
  • 8432524
• RefSeq identity
  • NM_004389
• Classification
  • Alpha catenins
• VEGA ID
  OTTHUMG00000152903

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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