Mouse anti Interleukin-1 beta (IL-1 §) antibody conjugated to FITC

• Catalog number
  L135M
• Price
  Please ask
• Size
  100 Tests

• Category
  Primary Antibodies
• Long description
  Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins.
• Antibody come from
  Human recombinant interleukin 1 beta (hIL- 1§)
• Other description
  Provided as sterile filtered solution in phosphate buffered saline with 0.08% sodium azide and 0.2% carrier protein. Protein A/G Chromatography
• Clone
  AS10
• Antigen antibody binding interaction
  Mouse anti Interleukin-1 beta (IL-1 §) antibody conjugated to FITC Antibody
• Antibody is raised in
  Mouse
• Antibody s reacts with
  Human
• Antibody s reacts with these species
  This antibody doesn't cross react with other species
• Antibody s specificity
  No Data Available
• Application
  Flow Cytometry
• Antibody s suited for
  Applications: Flow Cytometry: This antibody has been used at 10 µl per test (10^5-10^6 cells) to stain intracellular human IL-1§ expressed in Brefeldin A-treated monocytes and macrophages.
• Storage
  -20ºC
• Relevant references
  no information yet
• Protein number
  see ncbi
• Warnings
  This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
• Antibody s link
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• Properties
  If you buy Antibodies supplied by nordc they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. This nordc Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. nordc FITC is highly sensitive to pH extremes.
• Conjugation
  Anti-FITC Antibody
• Gene
  The Interleukin-1 family (IL-1 family) is a group of 11 cytokines, which plays a central role in the regulation of immune and inflammatory responses to infections or sterile insults. Rec. E. coli interleukin-1 for cell culture or antibody production.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus
• French translation
  anticorps

• Gene target
  Interleukin-1   beta   IL-1   conjugated  
• Gene symbol
  IL1A, IL1B, IL1F10, IL36B, IL36A, IL19, IL17F, IL36G, IL25, IL22
• Short name
  Mouse anti Interleukin-1 beta (IL-1 §) antibody conjugated FITC
• Technique
  Antibody, Mouse, anti, FITC, antibody to, antibodies against human proteins, antibodies for, antibody Conjugates, Fluorescein, mouses
• Host
  mouse
• Isotype
  IgG1
• Label
  FITC
• Species
  Mouses
• Alternative name
  Mouse antibody to Interleukin-1 b (Interleukin-1 §) (antibody to-) coupled to fluorecein
• Alternative technique
  antibodies, murine, fluorescine

Gene info

• Identity
  HGNC:5991
• Gene
  IL1A
• Long gene name
  interleukin 1 alpha
• Synonyms gene
  • IL1
• Synonyms
  • IL1F1
  • IL-1A
  • IL1-ALPHA
• Synonyms name
  • preinterleukin 1 alpha
  • hematopoietin-1
  • pro-interleukin-1-alpha
• GenBank acession
  • M28983
• Locus
  2q14.1
• Discovery year
  2001-06-22
• Entrez gene record
  3552
• Pubmed identfication
  • 8188271
  • 2989698
• RefSeq identity
  • NM_000575
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000131315

Gene info

• Identity
  HGNC:5992
• Gene
  IL1B
• Long gene name
  interleukin 1 beta
• Synonyms
  • IL1F2
  • IL-1B
  • IL1-BETA
• GenBank acession
  • M15330
• Locus
  2q14.1
• Discovery year
  1989-03-31
• Entrez gene record
  3553
• Pubmed identfication
  • 2954882
  • 2989698
• RefSeq identity
  • NM_000576
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000131344

Gene info

• Identity
  HGNC:15552
• Gene
  IL1F10
• Long gene name
  interleukin 1 family member 10
• Synonyms gene name
  • interleukin 1 family, member 10 (theta)
• Synonyms
  • FKSG75
  • IL-1HY2
  • IL-1F10
  • IL1-theta
  • MGC11983
  • MGC119832
  • MGC119833
• Synonyms name
  • FIL1- theta
  • interleukin-1 receptor antagonist FKSG75
• GenBank acession
  • AY026753
• Locus
  2q14.1
• Discovery year
  2002-08-02
• Entrez gene record
  84639
• Pubmed identfication
  • 11747621
  • 11991723
  • 11991722
• RefSeq identity
  • NM_173161
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000131339

Gene info

• Identity
  HGNC:15564
• Gene
  IL36B
• Long gene name
  interleukin 36 beta
• Synonyms gene
  • IL1F8
• Synonyms gene name
  • interleukin 1 family, member 8 (eta)
• Synonyms
  • FIL1
  • IL-1H2
  • IL-1F8
  • FILI-(ETA)
  • IL1-ETA
  • IL1H2
  • MGC126880
  • MGC126882
• GenBank acession
  • AF201833
• Locus
  2q14.1
• Discovery year
  2002-08-02
• Entrez gene record
  27177
• Pubmed identfication
  • 10625660
  • 10512743
  • 16646978
• RefSeq identity
  • NM_014438
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000131338

Gene info

• Identity
  HGNC:15562
• Gene
  IL36A
• Long gene name
  interleukin 36 alpha
• Synonyms gene
  • IL1F6
• Synonyms gene name
  • interleukin 1 family, member 6 (epsilon)
• Synonyms
  • FIL1
  • FIL1E
  • IL-1F6
  • IL1(EPSILON)
  • MGC129553
  • MGC129552
• GenBank acession
  • AF201831
• Locus
  2q14.1
• Discovery year
  2002-08-02
• Entrez gene record
  27179
• Pubmed identfication
  • 10625660
• RefSeq identity
  • NM_014440
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000153320

Gene info

• Identity
  HGNC:5990
• Gene
  IL19
• Long gene name
  interleukin 19
• Synonyms
  • IL-19
  • MDA1
  • ZMDA1
  • IL-10C
  • NG.1
• Synonyms name
  • melanoma differentiation associated protein-like protein
• GenBank acession
  • AF192498
• Locus
  1q32.1
• Discovery year
  2000-03-29
• Entrez gene record
  29949
• Pubmed identfication
  • 11196675
• RefSeq identity
  • NM_153758
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000036387

Gene info

• Identity
  HGNC:16404
• Gene
  IL17F
• Long gene name
  interleukin 17F
• Synonyms
  • IL-17F
  • ML-1
  • ML1
• GenBank acession
  • AF384857
• Locus
  6p12.2
• Discovery year
  2002-03-18
• Entrez gene record
  112744
• Pubmed identfication
  • 11591732
  • 11591768
• RefSeq identity
  • NM_052872
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000014845
• Locus Specific Databases
  • LRG_356

Gene info

• Identity
  HGNC:15741
• Gene
  IL36G
• Long gene name
  interleukin 36 gamma
• Synonyms gene
  • IL1F9
• Synonyms gene name
  • interleukin 1 family, member 9
• Synonyms
  • IL-1H1
  • IL-1RP2
  • IL-1F9
  • IL1H1
  • IL1E
• Synonyms name
  • interleukin-1 homolog 1
  • interleukin 1-related protein 2
  • interleukin-1 epsilon
• GenBank acession
  • AF200492
• Locus
  2q14.1
• Discovery year
  2002-08-02
• Entrez gene record
  56300
• Pubmed identfication
  • 10860666
  • 10744718
  • 11991722
  • 11991723
• RefSeq identity
  • NM_019618
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000131336

Gene info

• Identity
  HGNC:13765
• Gene
  IL25
• Long gene name
  interleukin 25
• Synonyms gene
  • IL17E
• Synonyms gene name
  • interleukin 17E
• Synonyms
  • IL-25
  • IL-17E
• GenBank acession
  • AF305200
• Locus
  14q11.2
• Discovery year
  2001-01-26
• Pubmed identfication
  • 11058597
  • 11754819
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000028749

Gene info

• Identity
  HGNC:14900
• Gene
  IL22
• Long gene name
  interleukin 22
• Synonyms
  • ILTIF
  • IL-21
  • zcyto18
  • IL-TIF
  • IL-D110
  • TIFa
  • TIFIL-23
  • IL-22
  • MGC79382
  • MGC79384
• Synonyms name
  • IL-10-related T-cell-derived inducible factor
• GenBank acession
  • AF279437
• Locus
  12q15
• Discovery year
  2001-03-12
• Entrez gene record
  50616
• Pubmed identfication
  • 10954742
  • 10875937
• RefSeq identity
  • NM_020525
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000169119
• Locus Specific Databases
  • LRG_1248

MeSH Data

• Name
  Cytophotometry
• Concept
  Scope note: A method for the study of certain organic compounds within cells, in situ, by measuring the light intensities of the selectively stained areas of cytoplasm. The compounds studied and their locations in the cells are made to fluoresce and are observed under a microscope.
• Tree numbers
  • E01.370.225.500.386
  • E05.196.712.516.600.240
  • E05.200.500.386
  • E05.242.386
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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