Target antigen
Syntaxin 1a
Clonality
Polyclonal antibody
Clone
Polyclonal antibody
Raised in
rabbit
Type of the antibody
IgG polyclonal antibody
Product form
freeze-dried
Reacts with species:
human, rat
Analyses
WB
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human Syntaxin 1a(1-28aa MKDRTQELRTAKDSDDDDDVAVTVDRDR), different from the related mouse and rat sequences by one amino acid.
Product configuration
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Purification
Immunogen affinity purified.
Solubilization
The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
Storage condtions
Keep the Syntaxin 1a Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
Tips
The Syntaxin 1a Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
Background
Syntaxin-1A is a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc). Syntaxins bind synaptotagminin a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. Syntaxin-1A is a key protein in ion channel regulation and synaptic exocytosis.
Related articles
1. "Entrez Gene: STX1A syntaxin 1A (brain)". 2. Bennett MK, García-Arrarás JE, Elferink LA, Peterson K, Fleming AM, Hazuka CD, Scheller RH (September 1993). "The syntaxin family of vesicular transport receptors".Cell 74 (5): 863–73.
Gene Name
STX1A
Protein Name
Syntaxin-1A
Gene Full Name
syntaxin 1A (brain)
Synonyms
EPIM antibody|Epimorphin antibody|EPM antibody|FP17469 antibody|HPC 1 antibody|Neuron specific antigen HPC 1 antibody|Neuron specific antigen HPC1 antibody|neuron-specific antigen HPC 1 antibody|P35 1 antibody|P35 1 antibody|STX 1 antibody|STX 1A antibody|STX1 antibody|STX1 antibody|STX1A antibody|Stx1b antibody|STX1B_HUMAN antibody|STX1B1 antibody|STX1B2 antibody|STX2 antibody|STX2A antibody|STX2B antibody|STX2C antibody|STX3 antibody|STX3A antibody|Syntaxin 1A antibody|Syntaxin 1A brain antibody|Syntaxin 1B antibody|Syntaxin 1B1 antibody|Syntaxin 1B2 antibody|Syntaxin 2 antibody|Syntaxin 3 antibody|Syntaxin 3A antibody|Syntaxin-1B antibody|Syntaxin-1B1 antibody|Syntaxin-1B2 antibody
Uniprot ID
Q16623
Entrez GeneID
6804
Properties
If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation
anticorps
