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Target antigen
Syntaxin 1a
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Clonality
Polyclonal antibody
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Clone
Polyclonal antibody
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Raised in
rabbit
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Type of the antibody
IgG polyclonal antibody
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Product form
freeze-dried
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Reacts with species
human, rat
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Analyses
WB
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Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human Syntaxin 1a(1-28aa MKDRTQELRTAKDSDDDDDVAVTVDRDR), different from the related mouse and rat sequences by one amino acid.
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Product configuration
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
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Purification
Immunogen affinity purified.
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Solubilization
The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
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Storage condtions
Keep the Syntaxin 1a Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
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Tips
The Syntaxin 1a Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
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Background
Syntaxin-1A is a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc). Syntaxins bind synaptotagminin a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. Syntaxin-1A is a key protein in ion channel regulation and synaptic exocytosis.
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Related articles
1. "Entrez Gene: STX1A syntaxin 1A (brain)". 2. Bennett MK, García-Arrarás JE, Elferink LA, Peterson K, Fleming AM, Hazuka CD, Scheller RH (September 1993). "The syntaxin family of vesicular transport receptors".Cell 74 (5): 863–73.
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Gene Name
STX1A
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Protein Name
Syntaxin-1A
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Gene Full Name
syntaxin 1A (brain)
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Synonyms
EPIM antibody|Epimorphin antibody|EPM antibody|FP17469 antibody|HPC 1 antibody|Neuron specific antigen HPC 1 antibody|Neuron specific antigen HPC1 antibody|neuron-specific antigen HPC 1 antibody|P35 1 antibody|P35 1 antibody|STX 1 antibody|STX 1A antibody|STX1 antibody|STX1 antibody|STX1A antibody|Stx1b antibody|STX1B_HUMAN antibody|STX1B1 antibody|STX1B2 antibody|STX2 antibody|STX2A antibody|STX2B antibody|STX2C antibody|STX3 antibody|STX3A antibody|Syntaxin 1A antibody|Syntaxin 1A brain antibody|Syntaxin 1B antibody|Syntaxin 1B1 antibody|Syntaxin 1B2 antibody|Syntaxin 2 antibody|Syntaxin 3 antibody|Syntaxin 3A antibody|Syntaxin-1B antibody|Syntaxin-1B1 antibody|Syntaxin-1B2 antibody
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Uniprot ID
Q16623
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Entrez GeneID
6804
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Properties
If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
