Caspase-2, CASP-2, Neural precursor cell expressed developmentally down-regulated protein 2, NEDD-2, Protease ICH-1
A cysteine protease involved in apoptosis
NCBI Gene ID #.
NCBI Gene Symbol
Activity (Specifications/test method)
10,000 – 13,000 units/mg
two large (19 kDa) and two small (12 kDa) subunits
Physical form description
Reconstitute to 1 unit per µl in PBS containing 15% glycerol.
Centrifuge the vial prior to opening.
For Research Use Only! Not to be used in humans
Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Recombinants or rec. proteins
caspase-2, H. sapiens recombinant