In 1X PBS, pH 7.4, with 0.09% sodium azide
Antigen affinity purified
Rabbit (Oryctolagus cuniculus)
Polyclonal (rabbit origin)
Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
Western blot: 1:1000
Titration of the CDC20B antibody may be required due to differences in protocols and secondary/substrate sensitivity.
This CDC20B antibodyis to be used only for research purposes and not for diagnostics..
The timely destruction of key regulators through ubiquitin-mediated proteolysis ensures the orderly progression of the cell cycle. The APC (anaphase-promoting complex) is a major component of this degradation machinery and its activation is required for the execution of critical events. CDC20B has been implicated as a meiosis specific activator of APC and is required for sporulation in budding yeast.
A portion of amino acids 11-39 from the human protein was used as the immunogen for this CDC20B antibody.
Aliquot the CDC20B antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.