CaspGLOW™ Red Active Caspase Staining Kit
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Catalog number
K190-100
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Price
Please ask
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Size
100 assays
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Description
Detects activated Caspases by FACS, FL or plate reader
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Summary
• Detection method- Fluorescence microscopy, fluorescence plate reader (Ex/Em = 540/570 nm) and Flow cytometry • Species reactivity- Mammalian • Kit size- Convenient sizes (25 and 100 assays) • Applications- Detection of activated caspases in living cells.
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Sample Type
Live cells
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Features Benefits
• Simple one-step procedure; takes only 1-2 hours • Fast and convenient • The red fluorescence label allows for direct detection of activated caspases in apoptotic cells
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Storage Conditions
-20°C
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Shipping Conditions
gel pack
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Shelf life
6-12 months
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Background
Activation of caspases plays a central role in apoptosis. The CaspGLOWTM Red Active Caspase Staining Kit provides a convenient means for detecting activated caspases in living cells. The assay utilizes a caspase family inhibitor VAD-FMK conjugated to sulfo-rhodamine (Red-VAD-FMK) as the fluorescent marker. Red-VAD-FMK is cell permeable, nontoxic, and irreversibly binds to activated caspases in apoptotic cells.
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Additional description
Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
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Conjugation
red dye
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Gene target
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Short name
CaspGLOW™ Red Active Caspase Staining Kit
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Label
Red
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Alternative name
CaspGLOW™ Red functionnal caspase coloring reagent
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Alternative technique
kits
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Alternative to gene target
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, C-Kit and CD117 and PBT and SCFR, KIT and IDBG-18980 and ENSG00000157404 and 3815, transferase activity, Extracellular, Kit and IDBG-172083 and ENSMUSG00000005672 and 16590, KIT and IDBG-642326 and ENSBTAG00000002699 and 280832
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MeSH Data
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Name
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Concept
Scope note:
Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.
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Tree numbers
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