-
Target
NFkB p65 (pSer468)
-
Conjugate
ATTO 488
-
Research Area s
Cancer, Apoptosis, Neuroscience, Neurodegeneration, Alzheimer's Disease, Cell Signaling, Epigenetics and Nuclear Signaling, Nuclear Signaling Pathways, NFkB Pathway, Cardiovascular System, Atherosclerosis, Vascular Inflammation, Inflammatory Mediators, Cell Signaling, Metabolism
-
Alternative Name s
p65 Antibody, RELA Antibody, NFkB p65 Antibody, NF- kappaB p65 Antibody, p65 NF kappaB Antibody, OTTHUMP00000233476 Antibody, OTTHUMP00000233473 Antibody, OTTHUMP00000233475 Antibody, V rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B cells 3, p65 Antibody, p65 NFkB Antibody, RELA Antibody, Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 Antibody, Avian reticuloendotheliosis viral (v rel) oncogene homolog A Antibody, v rel reticuloendotheliosis viral oncogene homolog A (avian) Antibody, Nuclear factor of kappa light polypeptide gene enhancer in B cells 3 Antibody, Transcription factor p65 Antibody, OTTHUMP00000233474 Antibody, NF kappa B p65delta3 Antibody, NFKB3 Antibody, TF65_HUMAN Antibody, OTTHUMP00000233900 Antibody, v rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide gene enhancer in B cells 3 (p65)) Antibody, Nuclear Factor NF Kappa B p65 Subunit Antibody, V rel avian reticuloendotheliosis viral oncogene homolog A Antibody, Nuclear factor NF-kappa-B p65 subunit Antibody, MGC131774 Antibody
-
Category
Antibodies
-
Product Type
Polyclonal
-
Immunogen
Synthetic phospho-peptide from human NFkB p65 around the phosphorylation site of serine 468 (pSer468).
-
Immunogen Species
Human
-
Accession Number
NP_001138610.1
-
Gene ID
5970
-
Swiss Prot
Q04206
-
Applications
WB, IHC, IP
-
Host Species
Rabbit
-
Species Reactivity
Human, Mouse, Rat
-
Antibody Dilution
WB (1:250-1:1000); IHC (1:25-1:100); IP (Various dilutions); optimal dilutions for assays should be determined by the user.
-
Purification
Peptide Affinity Purified
-
Storage Buffer
PBS, pH 7.4, 150mM NaCl, 50% glycerol, 0.02% sodium azide
-
Specificity
Detects endogenous levels of NFkB p65 only when phosphorylated at serine 468 (pSer468). Detects a band at ~75 kDa.
-
Storage Temperature
-20ºC
-
Shipping Temperature
Blue Ice or 4ºC
-
Cellular Localization
Nucleus, Cytoplasm, Cytosol, Nuclear Chromatin, Nucleoplasm, Transcription Factor Complex, I-Kappab/Nf-Kappab Complex, Nf-Kappab P50/P65 Complex
-
Field of Use
For in vitro research use only.
-
-
-
Gross Weight kg
1.4
-
Net Weight g
0.1
-
Properties
If you buy Antibodies supplied by StressMarq they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
Gene
NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) is a protein complex that controls transcription of DNA, cytokine production and cell survival. NF-κB is found in almost all animal cell types and is involved in cellular responses to stimuli such as stress, cytokines, free radicals, ultraviolet irradiation, oxidized LDL, and bacterial or viral antigens. NF-κB plays a key role in regulating the immune response to infection (κ light chains are critical components of immunoglobulins). Incorrect regulation of NF-κB has been linked to cancer, inflammatory and autoimmune diseases, septic shock, viral infection, and improper immune development. NF-κB has also been implicated in processes of synaptic plasticity and memory
-
French translation
anticorps
