- Catalog numberSPC-1105D-A594
- Product nameRabbit Anti-Human ARAF Polyclonal: ATTO 594
- Size100 µl
- PriceAsk For Price
- LabelATTO 594
- ImmunogenSynthetic peptide of human ARaf (AA300-314)
- Antibody s targetHuman ARAF
- Antibody s full descriptionRabbit Anti-Human ARAF Polyclonal
- Antibody s categoryPolyclonal Antibodies
- Antibody s other nameA raf 1 antibody, A Raf proto oncogene serine/threonine protein kinase antibody, ARAF 1 antibody, Araf antibody, ARaf proto oncogene serine/threonine protein kinase antibody, ARAF_HUMAN antibody, ARAF1 antibody, PKS 2 antibody, PKS antibody, PKS2 antibody, RAFA 1 antibody, RAFA1 antibody, Ras binding protein DA Raf antibody, Serine/threonine-protein kinase A-Raf antibody, v raf murine sarcoma 3611 viral oncogene homolog antibody
- Verified applicationsWB, AM
- Raised inRabbit
- IsotypeImmunoglobulin
- Antibody s reactivityHuman, Mouse
- Antibody s recommended dilutions for useWB (1:250); optimal dilutions for assays should be determined by the user.
- Antibody s purified fromPeptide Affinity Purified
- Recommended buffer for storagePBS pH7.4, 50% glycerol, 0.025% Thimerosal
- Antibody s concentrationSee included datasheet or contact our support service
- Antibody s specificityDetects 68 kDa.
- Storage recommendations-20°C
- Shipping recommendationsBlue Ice or 4°C
- Certificate of analysisA 1:250 dilution of SPC-1105 was sufficient for detection of ARAF in 10 µg of HeLa cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
- Antibody in cellCytosol
- Tissue specificityPredominantly in urogenital tissues.
- Scientific contextARAF is a tyrosine kinase-like kinase of the Raf family. It is involved in the transduction of mitogenic signals from the cell membrane receptors via Ras and MEK1/2 to the nucleus. It has been implicated in playing a role in the postsynaptic responses of hippocampal neuron. It is inhibited by Nexavar/Sorafenib (IC50>50 nM).
- BibliographyRefer to PubMed
- Released date29/Aug/2016
- NCBI numberNP_001645
- Gene number369
- Protein numberP10398
- PubMed numberRefer to PubMed
- Tested applicationsTo be tested
- Tested reactivityTo be tested
- Antibody s datasheetContact our support service to receive datasheet or other technical documentation.
- Representative figure linkNo Data Available
- Warning informationNon-hazardous
- Country of productionCanada
- Total weight kg1.4
- Net weight g0.1
- Stock availabilitIn Stock
- Other related products
- Gene targetARAF ATTO 594
- Identity:HGNC:646
- Gene:ARAF
- Long gene name:A-Raf proto-oncogene, serine/threonine kinase
- Synonyms gene name:v-raf murine sarcoma 3611 viral oncogene homolog 1
- Discovery year:1986-01-01
- Entrez gene record:369
- Classification:Mitogen-activated protein kinase kinase kinases, RAF family
- VEGA ID:OTTHUMG00000021446
- Gene symbolARAF
- HostRabbit, Rabbits
- isotype filter
- Immunoglobulin
- Short nameRabbit Anti- ARAF Polyclonal: ATTO 594
- label filter
- ATTO 594
- technique filter
- anti-Human
- Polyclonal
- Rabbit
- anti-
- anti
- Techniqueanti-Human, Polyclonal, Rabbit, anti-, anti, antibody to, antibodies, antibodies against human proteins, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
- Alternative techniquepolyclonals, rabbit-anti, antibodies
Gene info
Locus Specific Databases:Global Variome shared LOVD