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Mouse Anti-Rat Cav1.3 Monoclonal IgG2a Kappa, Clone S48A-9

  • Catalog number
    SMC-301D-PCP
  • Product name
    Mouse Anti-Rat Cav1.3 Monoclonal IgG2a Kappa, Clone S48A-9
  • Size
    100 µg
  • Label
    PerCP
  • Clone
    S48A-9
  • Immunogen
    Fusion protein amino acids 859-875 of rat Cav1.3
  • Antibody s full description
    Mouse Anti-Rat Cav1.3 Monoclonal IgG2a Kappa Antibody, Clone: S48A-9: PerCP
  • Antibody s category
    Monoclonal Antibodies
  • Antibody s other name
    alpha-1 polypeptide Antibody, CAC1D_HUMAN Antibody, CACH3 Antibody, CACN4 Antibody, CACNA 1D Antibody, Cacna1d Antibody, CACNL1A2 Antibody, Calcium channel Antibody, Calcium channel L type alpha 1 polypeptide isoform 2 Antibody, Calcium channel neuroendocrine/brain type alpha 1 subunit Antibody, Calcium channel voltage dependent L type alpha 1D subunit Antibody, CCHL1A2 Antibody, isoform 2 Antibody, L type Antibody, Voltage dependent L type calcium channel subunit alpha 1D Antibody, Voltage gated calcium channel alpha 1 subunit Antibody, Voltage gated calcium channel alpha subunit Cav1.3 Antibody, Voltage gated calcium channel subunit alpha Cav1.3 Antibody, Voltage-dependent L-type calcium channel subunit alpha-1D Antibody, Voltage-gated calcium channel subunit alpha Cav1.3 Antibody
  • Raised in
    Mouse
  • Isotype
    IgG2a Kappa, IgG2a
  • Antibody s target
    Cav1.3
  • Primary research fields
    Neuroscience, Ion Channels, Calcium Channels, Voltage-Gated Calcium Channels , Cancer, Cell Signaling
  • Brandname
    None
  • Antibodies applications
    WB, IHC, ICC/IF, IP , AM
  • Antibody s reactivity
    Human, Mouse, Rat
  • Antibody s dilutions
    WB (1:1000), IHC (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
  • Purity
    Protein G Purified
  • Antibody buffer for storage
    PBS pH7.4, 50% glycerol, 0.09% sodium azide
  • Antibody s concentration
    1 mg/ml
  • Antibody s specificity
    Detects ~250kDa. No cross-reactivity against Cav1.2.
  • Storage recommendations
    -20ºC
  • Shipping recommendations
    Blue Ice or 4ºC
  • Antibody certificate of analysis
    1 µg/ml of SMC-301 was sufficient for detection of Cav1.3 in 10 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
  • Antibody in cell
    Membrane , Cell Membrane
  • Tissue specificity
    See included datasheet or contact our support service
  • Scientific context
    CaV1.3, also known as the calcium channel, voltage-dependent, L type, alpha 1D subunit (CACNA1D), is a human gene. CaV1.3 subunits are primarily expressed in neurons and neuroendocine cells. Some studies suggest however that CaV1.3 is also found in the atria, and may figure prominently in atrial arrhythmias (1). CaV1.3 also carries the primary sensory receptors of the mammalian cochlea, and are also expressed in the electromotile outer hair cells (2).
  • Bibliography
    1. Zhang Z., et al. (2005) Circulation 112: 1936-1944. 2. Johnson S.L. and Marcotti W. (2008) The Journal of Physiology. 586: 1029-1042.
  • Released date
    15-Aug-2009
  • Tested applications
    To be tested
  • Tested reactivity
    To be tested
  • NCBI number
    NP_058994.1
  • Gene number
    29716
  • Protein number
    P27732
  • Antibody s datasheet
    Contact our support service
  • Representative figure link
    Representative_figure_link
  • Representative figure legend
    Immunohistochemistry analysis using Mouse Anti-CaV1.3 Calcium Channel Monoclonal Antibody, Clone S48A-9 (SMC-301). Tissue: backskin. Species: Mouse. Fixation: Bouin's Fixative and paraffin-embedded. Primary Antibody: Mouse Anti-CaV1.3 Calcium Channel Monoclonal Antibody (SMC-301) at 1:100 for 1 hour at RT. Secondary Antibody: FITC Goat Anti-Mouse (green) at 1:50 for 1 hour at RT. Immunohistochemistry analysis using Mouse Anti-CaV1.3 Calcium Channel Monoclonal Antibody, Clone S48A-9 (SMC-301). Tissue: hippocampus. Species: Human. Fixation: Bouin's Fixative and paraffin-embedded. Primary Antibody: Mouse Anti-CaV1.3 Calcium Channel Monoclonal Antibody (SMC-301) at 1:1000 for 1 hour at RT. Secondary Antibody: FITC Goat Anti-Mouse (green) at 1:50 for 1 hour at RT. Mouse Anti-CaV1.3 Calcium Channel Antibody [S48A-9] used in Immunohistochemistry (IHC) on Mouse backskin (SMC-301) Mouse Anti-CaV1.3 Calcium Channel Antibody [S48A-9] used in Immunohistochemistry (IHC) on Human hippocampus (SMC-301)
  • Warning information
    Non-hazardous
  • Country of production
    Canada
  • Total weight kg
    1.4
  • Net weight g
    0.1
  • Stock availability
    In Stock
  • Other related products
    Other_related_products
  • Alternative to gene target
    • [ "caveolin 1, caveolae protein, 22kDa", "BSCL3 and CGL3 and LCCNS and MSTP085 and PPH3 and VIP21", "CAV1 and IDBG-37314 and ENSG00000105974 and 857", "nitric-oxide synthase binding", "Cell surfaces", "Cav1 and IDBG-129000 and ENSMUSG00000007655 and 12389", "CAV1 and IDBG-632834 and ENSBTAG00000017869 and 281040" ]
  • Gene target
    Cav1 3 Monoclonal IgG2a Kappa S48A-9
    • Gene info
    Gene info
    • Identity:HGNC:37551
    • Gene:PIRC47
    • Long gene name:piwi-interacting RNA cluster 47
    • Discovery year:2009-11-05
    • Entrez gene record:100313859
    • Pubmed identification:17881367
    • Classification:Piwi-interacting RNA clusters
    Gene info
    • Identity:HGNC:37542
    • Gene:PIRC38
    • Long gene name:piwi-interacting RNA cluster 38
    • Discovery year:2009-11-05
    • Entrez gene record:100313788
    • Pubmed identification:17881367
    • Classification:Piwi-interacting RNA clusters
    Gene info
    • Identity:HGNC:37547
    • Gene:PIRC43
    • Long gene name:piwi-interacting RNA cluster 43
    • Discovery year:2009-11-05
    • Entrez gene record:100313857
    • Pubmed identification:17881367
    • Classification:Piwi-interacting RNA clusters
    Gene info
    • Identity:HGNC:37549
    • Gene:PIRC45
    • Long gene name:piwi-interacting RNA cluster 45
    • Discovery year:2009-11-05
    • Entrez gene record:100313813
    • Pubmed identification:17881367
    • Classification:Piwi-interacting RNA clusters
    Gene info
    • Identity:HGNC:37541
    • Gene:PIRC37
    • Long gene name:piwi-interacting RNA cluster 37
    • Discovery year:2009-11-05
    • Entrez gene record:100313812
    • Pubmed identification:17881367
    • Classification:Piwi-interacting RNA clusters
  • Gene symbol
    RNU6-9, PIRC47, PIRC38, PIRC43, PIRC45, PIRC37
  • Host
    mouse
  • isotype filter
    • IgG2a Kappa
  • Short name
    Mouse Anti- Cav1 3 Monoclonal IgG2a Kappa, Clone S48A-9
  • label filter
    • PerCP
  • Clone name
    S48A-9
  • technique filter
    • anti-
    • Mouse
    • anti
  • Technique
    anti-, Mouse, anti, antibody to, antibodies, Monoclonals or monoclonal antibodies, mouses
  • Alternative technique
    murine, antibodies