• Catalog number
    SPC-218A-P594
  • Product name
    Goat Anti-Human Nrf2 Polyclonal: PE/ATTO 594
  • Size
    50 µg
  • Label
    PE/ATTO 594
  • Immunogen
    Peptide derived from human Nrf2 protein (a.a. 445-458)
  • Antibody s target
    Human Nrf2
  • Antibody s full description
    Goat Anti-Human Nrf2 Polyclonal
  • Primary research fields
    Cancer, Oxidative Stress, Cell Signaling, Epigenetics, Cardiovascular System, Heart
  • Antibody s category
    Polyclonal Antibodies
  • Antibody s other name
    Erythroid derived 2 antibody, HEBP1 antibody, like 2 antibody, NF E2 related factor 2 antibody, NF-E2-related factor 2 antibody, NF2L2_HUMAN antibody, NFE2 related factor 2 antibody, NFE2-related factor 2 antibody, NFE2L2 antibody, Nrf 2 antibody, NRF2 antibody, Nuclear factor (erythroid derived 2) like 2 antibody, Nuclear factor antibody, nuclear factor erythroid 2 like 2 antibody, Nuclear factor erythroid 2 related factor 2 antibody, Nuclear factor erythroid 2-related factor 2 antibody, Nuclear factor erythroid derived 2 like 2 antibody
  • Verified applications
    WB, ELISA
  • Raised in
    Goat
  • Isotype
    Immunoglobulin
  • Antibody s reactivity
    Human, Mouse, Rat, Bovine, Dog, Pig
  • Antibody s recommended dilutions for use
    WB (1:1500), ELISA (1:64000); optimal dilutions for assays should be determined by the user.
  • Antibody s purified from
    Protein A Purified
  • Recommended buffer for storage
    TBS pH7.3, 0.02% sodium azide, 0.5% BSA
  • Antibody s concentration
    See included datasheet or contact our support service
  • Antibody s specificity
    Aggrephagy associated oxidative stress response transcription factor.
  • Storage recommendations
    4°C
  • Shipping recommendations
    Blue Ice or 4°C
  • Certificate of analysis
    A 1:1500 dilution of SPC-218 was sufficient for detection of Nrf2 in 35 µg of human lung lysate by electrochemiluminescence analysis using donkey anti-goat IgG:HRP as the secondary antibody.
  • Antibody in cell
    Cytoplasm, Nucleus
  • Tissue specificity
    See included datasheet or contact our support service.
  • Scientific context
    Nrf2 is a transcription factor which plays a role in the oxidative stress response. Under normal cellular conditions, it is sequestered in the cytoplasm by Keap1 and Cullin3. When under oxidative stress, Nrf2 is release from Keap1 by p62 and is translocated to the nucleus where it acts as a transcription factor for the expression of oxidative stress-related products.
  • Bibliography
    1. Itoh K., Wakabayashi N., Katoh Y., Ishii T., Igarashi K., Engel J., et al. (1999) Genes Dev. 13(1): 76-86.
  • Released date
    12/Jun/2014
  • NCBI number
    NP_006155.16
  • Gene number
    4794
  • Protein number
    Q16250
  • PubMed number
    Refer to PubMed
  • Tested applications
    To be tested
  • Tested reactivity
    To be tested
  • Antibody s datasheet
    Contact our support service to receive datasheet or other technical documentation.
  • Representative figure link
    No Data Available
  • Warning information
    Non-hazardous
  • Country of production
    Canada
  • Total weight kg
    1.4
  • Net weight g
    0.05
  • Stock availabilit
    In Stock
  • Other related products
  • Gene target
    Nrf2 PE/ATTO 594
  • Host
    Goat, The goat polyclonal antibodies are directed against human genes or rabbit or mouse IgGs (H +L) chain primary antibodies and conjugated for detection. It are very good secondary antibodies that are affinity purified and have a good affinity themselves too. Often KLH is coupled to the antigen so anti KLH can be present in the vial.
  • isotype filter
    • Immunoglobulin
  • Short name
    Goat Anti- Nrf2 Polyclonal: PE/ATTO 594
  • label filter
    • PE ATTO 594
  • technique filter
    • anti-Human
    • Polyclonal
    • anti-
    • anti
    • Goat
  • Technique
    anti-Human, Polyclonal, anti-, anti, Goat, antibody to, antibodies, antibodies against human proteins, goats, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
  • Alternative technique
    polyclonals, antibodies, caprine