- Catalog numberSPC-218A-P594
- Product nameGoat Anti-Human Nrf2 Polyclonal: PE/ATTO 594
- Size50 µg
- PriceAsk For Price
- LabelPE/ATTO 594
- ImmunogenPeptide derived from human Nrf2 protein (a.a. 445-458)
- Antibody s targetHuman Nrf2
- Antibody s full descriptionGoat Anti-Human Nrf2 Polyclonal
- Primary research fieldsCancer, Oxidative Stress, Cell Signaling, Epigenetics, Cardiovascular System, Heart
- Antibody s categoryPolyclonal Antibodies
- Antibody s other nameErythroid derived 2 antibody, HEBP1 antibody, like 2 antibody, NF E2 related factor 2 antibody, NF-E2-related factor 2 antibody, NF2L2_HUMAN antibody, NFE2 related factor 2 antibody, NFE2-related factor 2 antibody, NFE2L2 antibody, Nrf 2 antibody, NRF2 antibody, Nuclear factor (erythroid derived 2) like 2 antibody, Nuclear factor antibody, nuclear factor erythroid 2 like 2 antibody, Nuclear factor erythroid 2 related factor 2 antibody, Nuclear factor erythroid 2-related factor 2 antibody, Nuclear factor erythroid derived 2 like 2 antibody
- Verified applicationsWB, ELISA
- Raised inGoat
- IsotypeImmunoglobulin
- Antibody s reactivityHuman, Mouse, Rat, Bovine, Dog, Pig
- Antibody s recommended dilutions for useWB (1:1500), ELISA (1:64000); optimal dilutions for assays should be determined by the user.
- Antibody s purified fromProtein A Purified
- Recommended buffer for storageTBS pH7.3, 0.02% sodium azide, 0.5% BSA
- Antibody s concentrationSee included datasheet or contact our support service
- Antibody s specificityAggrephagy associated oxidative stress response transcription factor.
- Storage recommendations4°C
- Shipping recommendationsBlue Ice or 4°C
- Certificate of analysisA 1:1500 dilution of SPC-218 was sufficient for detection of Nrf2 in 35 µg of human lung lysate by electrochemiluminescence analysis using donkey anti-goat IgG:HRP as the secondary antibody.
- Antibody in cellCytoplasm, Nucleus
- Tissue specificitySee included datasheet or contact our support service.
- Scientific contextNrf2 is a transcription factor which plays a role in the oxidative stress response. Under normal cellular conditions, it is sequestered in the cytoplasm by Keap1 and Cullin3. When under oxidative stress, Nrf2 is release from Keap1 by p62 and is translocated to the nucleus where it acts as a transcription factor for the expression of oxidative stress-related products.
- Bibliography1. Itoh K., Wakabayashi N., Katoh Y., Ishii T., Igarashi K., Engel J., et al. (1999) Genes Dev. 13(1): 76-86.
- Released date12/Jun/2014
- NCBI numberNP_006155.16
- Gene number4794
- Protein numberQ16250
- PubMed numberRefer to PubMed
- Tested applicationsTo be tested
- Tested reactivityTo be tested
- Antibody s datasheetContact our support service to receive datasheet or other technical documentation.
- Representative figure linkNo Data Available
- Warning informationNon-hazardous
- Country of productionCanada
- Total weight kg1.4
- Net weight g0.05
- Stock availabilitIn Stock
- Other related products
- Gene targetNrf2 PE/ATTO 594
- HostGoat, The goat polyclonal antibodies are directed against human genes or rabbit or mouse IgGs (H +L) chain primary antibodies and conjugated for detection. It are very good secondary antibodies that are affinity purified and have a good affinity themselves too. Often KLH is coupled to the antigen so anti KLH can be present in the vial.
- isotype filter
- Immunoglobulin
- Short nameGoat Anti- Nrf2 Polyclonal: PE/ATTO 594
- label filter
- PE ATTO 594
- technique filter
- anti-Human
- Polyclonal
- anti-
- anti
- Goat
- Techniqueanti-Human, Polyclonal, anti-, anti, Goat, antibody to, antibodies, antibodies against human proteins, goats, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
- Alternative techniquepolyclonals, antibodies, caprine