- Catalog numberCSB-PA842754LD01HU_50ug
- Product nameRabbit Anti Human TWNK Antibody-Biotin
- Size50ug
- PriceAsk For Price
- Long nameRabbit Antibody against Human TWNK, Biotin
- Short nameAnti-TWNK
- Synonym nameTWNK Human Antibody
- HostRabbit, Rabbits
- Species reactivityHuman
- Tested applications recommended dilutionsELISA
- ConjugationBiotin
- Antibody isotypeIgG
- UniProt IDQ96RR1
- FormatLiquid, diluted in buffer
- Buffer compositionPreservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
- Purity>95%
- Purification methodProtein G purified
- Antibody categoryPolyclonal Antibodies
- Immunogen typeRecombinant Human Twinkle protein, mitochondrial protein (559-684AA)
- Immunogen speciesHuman
- AliasTwinkle protein, mitochondrial, Progressive external ophthalmoplegia 1 protein, T7 gp4-like protein with intramitochondrial nucleoid localization, T7-like mitochondrial DNA helicase, Twinkle mtDNA helicase, TWNK
- BackgroundInvolved in mitochondrial DNA (mtDNA) metabolism. Could function as an adenine nucleotide-dependent DNA helicase. Function inferred to be critical for lifetime maintenance of mtDNA integrity. In vitro, forms in combination with POLG, a processive replication machinery, which can use double-stranded DNA (dsDNA) as template to synthesize single-stranded DNA (ssDNA) molecules. May be a key regulator of mtDNA copy number in mammals.
- ClonalityPolyclonal antibody
- Shipping and storageTWNK Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
- Short name of the antigenTwinkle protein, mitochondrial
- Gene targetTWNK -
- Identity:HGNC:1160
- Gene:TWNK
- Long gene name:twinkle mtDNA helicase
- Synonyms gene name:infantile onset spinocerebellar ataxia (autosomal recessive), chromosome 10 open reading frame 2
- Synonyms:PEO, PEO1TWINKLEFLJ21832TWINL
- Discovery year:2000-08-11
- Entrez gene record:56652
- Pubmed identification:11431692, 10645945, 16135556
- RefSeq identity:NM_021830
- Classification:DNA helicases
- VEGA ID:OTTHUMG00000018917
- Gene symbolTWNK
- LabelBiotin
- label filter
- Biotin
- technique filter
- anti human
- Antibody
- Rabbit
- anti
- Techniqueanti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for
- Alternative techniqueantibodies, rabbit-anti