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Dissolution Media - Ready to Use accreditated USP & EP - Hydrochloric Acid 0.1N

  • Catalog number
    bs-5320R-A555
  • Product name
    EGFR (Ser768) Antibody, ALEXA FLUOR 555
  • Size
    100ul
  • Short name
    Anti-EGFR Ser768
  • Long name
    EGFR (Ser768) Polyclonal Antibody, ALEXA FLUOR 555 Conjugated
  • Also known as
    Anti-EGFR Ser768 PAb ALEXA FLUOR 555
  • Category
    Conjugated Primary Antibodies
  • Conjugated with
    ALEXA FLUOR® 555
  • Host Organism
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    EGFR Ser768
  • Specificity
    This is a highly specific antibody against EGFR Ser768.
  • Modification
    Phosphorylation
  • Modification Site
    Ser768
  • Clonality
    Polyclonal
  • Clone
    Polyclonal antibody
  • Isotype
    Immunoglobulin G (IgG)
  • Concentration
    1ug per 1ul
  • Source
    KLH conjugated synthetic phosphopeptide derived from human EGFR around the phosphorylation site of Ser768
  • Gene ID Number
    1956
  • Tested applications
    IF(IHC-P)
  • Recommended dilutions
    IF(IHC-P)(1:50-200)
  • Crossreactivity
    Human, Mouse, Rat
  • Cross reactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Background of the antigen
    Protein kinases are enzymes that transfer a phosphate group from a phosphate donor onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. The protein kinase family is one of the largest families of proteins in eukaryotes, classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. Epidermal Growth factor receptor (EGFR) is the prototype member of the type 1 receptor tyrosine kinases. EGFR overexpression in tumors indicates poor prognosis and is observed in tumors of the head and neck, brain, bladder, stomach, breast, lung, endometrium, cervix, vulva, ovary, esophagus, stomach and in squamous cell carcinoma.
  • Purification
    Purified by Protein A.
  • Storage conditions
    Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
  • Excitation emission
    553nm/568nm
  • Synonyms
    EGFR; Avian erythroblastic leukemia viral v erb b oncogene homolog; Avian erythroblastic leukemia viral verbb oncogene homolog; Cell growth inhibiting protein 40; Cell proliferation inducing protein 61; EGF R; EGFR; Epidermal growth factor receptor avian erythroblastic leukemia viral v erb b oncogene homolog; Epidermal growth factor receptor erythroblastic leukemia viral v erb b oncogene homolog avian; Epidermal growth factor receptor; erbb 1; Erbb; Erbb1; HER1; mENA; Oncogene ERBB; PIG61; Receptor tyrosine protein kinase ErbB 1; Receptor tyrosine protein kinase ErbB1; Urogastrone; wa2; Wa5.
  • Alternative to gene target
    • [ "epidermal growth factor receptor", "ERBB and ERBB1 and HER1 and mENA and PIG61", "EGFR and IDBG-16933 and ENSG00000146648 and 1956", "transferase activity", "nuclei", "Egfr and IDBG-151194 and ENSMUSG00000020122 and 13649", "EGFR and IDBG-644035 and ENSBTAG00000011628 and 407217" ]
  • Gene target
    EGFR Ser768
    • Gene info
    Gene info
    • Identity:HGNC:54482
    • Gene:EGILA
    • Long gene name:EGFR interacting lncRNA
    • Synonyms:Lnc-EGFR
    • Discovery year:2019-09-27
    • Pubmed identification:28541302
    • Classification:Long non-coding RNAs with non-systematic symbols
    Gene info
    Locus Specific Databases:LRG_304
    Gene info
  • Gene symbol
    EGFR-AS1, EGILA, EGFR, RHBDF1
  • isotype filter
    • Immunoglobulin G IgG
  • Label
    ALEXA FLUOR 555
  • label filter
    • ALEXA FLUOR 555
  • technique filter
    • Antibody
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Alternative technique
    antibodies