anti-RICK Antibody

• Catalog number
  2075
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  RICK Antibody: Apoptosis is mediated by death domain (DD) and/or caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. DD-containing serine/threonine kinase RIP regulates Fas-induced apoptosis. A novel CARD-containing serine/threonine kinase was recently identified and designated RICK/RIP2/CARDIAK for RIP-like interacting CLARP kinase, receptor interacting protein-2, and CARD-containing ICE associated kinase, respectively. RICK contains an N-terminal kinase catalytic domain and a C-terminal CARD domain. Overexpression of RICK induced apoptosis and activation of NF-kB and JNK. RICK interacts with members of the TRAF family, CLARP and caspase-1. Thus, RICK represents a novel kinase that regulates TNF and Fas induced-apoptosis and that is involved in the generation of proinflammatory cytokine IL-1β. The messenger RNA of RICK is expressed in multiple human tissues.
• Gene names
  RICK Antibody: CCK, RICK, RIP2, CARD3, GIG30, CARDIAK, UNQ277/PRO314/PRO34092, CARD-containing interleukin-1 beta-converting enzyme-associated kinase, CARD-containing IL-1 beta ICE-kinase
• Antibodie s label
  unlabelled serum
• Purity
  RICK Antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Antigen
  RICK antibody was made against a peptide corresponding to amino acids near the amino terminus of human RICK.
• Immuno application
  ELISA, Western Blot, immuno-cyto-chemistry
• Antibody advice
  RICK antibody can be used for detection of RICK by Western blot at 1 ug/mL. An approximately 60 kDa band can be detected. Antibody can also be used for immunocytochemistry starting at 10 ug/mL.
• Suspention pH azide
  RICK Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  RICK antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human, Mouse, Rat
• Omim nr
  20455217
• Ncbi nr
  O43353
• KDa
  60 kDa
• Vial with antibody
  in solution
• NCBI GENE nr
  8767
• GENE symbol
  RIPK2
• Antigene name
  receptor-interacting serine-threonine kinase 2
• Source
  Homo sapiens
• Protein nr
  O43353
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  RICK  
• Gene symbol
  RIPK2
• Short name
  anti-RICK Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toRICK (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:10020
• Gene
  RIPK2
• Long gene name
  receptor interacting serine/threonine kinase 2
• Synonyms gene name
  • receptor-interacting serine-threonine kinase 2
• Synonyms
  • RICK
  • RIP2
  • CARDIAK
  • CARD3
• GenBank acession
  • AC004003
• Locus
  8q21.3
• Discovery year
  1999-05-07
• Entrez gene record
  8767
• Pubmed identfication
  • 9575181
  • 9705938
• Classification
  • Caspase recruitment domain containing
• VEGA ID
  OTTHUMG00000163809

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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