- Catalog numberR32003
- Product nameTissue Factor Antibody / CD142
- Size0.1mg
- PriceAsk For Price
- Short nameAnti-Tissue Factor / CD142
- CategoryAntibody
- Concentration0.5mg/ml if reconstituted with 0.2ml sterile DI water
- FormAntigen affinity purified
- ConjugationUnconjugated
- ClonePolyclonal antibody
- Recognised antigenTissue Factor / CD142
- Host animalRabbit (Oryctolagus cuniculus)
- ClonalityPolyclonal (rabbit origin)
- IsotypeRabbit IgG
- Species reactivityMouse (Mus musculus) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
- Tested applicationsWB
- Recommended dilutionsWestern blot: 0.1-0.5ug/ml
- NotesOptimal dilution of the CD142 antibody should be determined by the researcher.
- Intented useThis CD142 antibodyis to be used only for research purposes and not for diagnostics..
- UniprotP20352
- PurityAntigen affinity
- DescriptionTissue factor also called platelet tissue factor, factor III, or CD142. This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alternate splicing results in multiple transcript variants.
- ImmunogenAmino acids 29-294 of mouse CD142/F3 were used as the immunogen for the CD142 antibody.
- StorageAfter reconstitution, the CD142 antibody may be kept for up to one month refrigerated at +4 degrees C.For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
- Gene targetTissue Factor / CD142
- Identity:HGNC:3541
- Gene:F3
- Long gene name:coagulation factor III, tissue factor
- Synonyms gene name:coagulation factor III (thromboplastin, tissue factor)
- Synonyms:CD142TF
- Discovery year:2001-06-22
- Entrez gene record:2152
- RefSeq identity:NM_001993
- Classification:CD molecules
- VEGA ID:OTTHUMG00000010716
- Gene symbolF3
- isotype filter
- Rabbit IgG
- technique filter
- Antibody
- tissue
- TechniqueAntibody, tissue, antibodies against human proteins, antibodies for, tissues
- Alternative techniqueantibodies, tissues
- Tissuetissue
- tissue filter
- tissue
Gene info
Locus Specific Databases:LRG_552