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SIN1 Antibody

  • Catalog number
    N1067-100UG
  • Product name
    SIN1 Antibody
  • Size
    0.1mg
  • Price
    Ask For Price
  • Contact us
    SIN1 Antibody
  • Short name
    Anti-SIN1
  • Category
    Antibody
  • Concentration
    0.5 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
  • Form
    Purified
  • Conjugation
    Unconjugated
  • Clone
    Polyclonal antibody
  • Recognised antigen
    SIN1
  • Host animal
    Rabbit (Oryctolagus cuniculus)
  • Clonality
    Polyclonal (rabbit origin)
  • Isotype
    Rabbit IgG
  • Species reactivity
    Human (Homo sapiens), Mouse (Mus musculus), Rat, Dog ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
  • Tested applications
    WB
  • Recommended dilutions
    Western blot: 1-3ug/ml
  • Notes
    Provided assay concentrations are suggestions only, SIN1 antibody titration may be required for optimal results.
  • Added buffer
    1X Phosphate Buffered Saline (PBS), pH 7.4
  • Intented use
    This SIN1 antibodyis to be used only for research purposes and not for diagnostics..
  • Gene ID
    79109
  • Purity
    This antibody was purified by Protein A method
  • Description
    mTOR, or Mammalian target of rapamycin, a large protein kinase, is a regulator of cell growth and survival via its mTORC1 (mTOR + GBL + Raptor) and mTORC2 (mTOR + GBL + SIN1 + Rictor) complexes. SIN1 is an essential component of mTORC2, which activates Akt by phosphorylating Ser473. Phosphorylation of SIN1 at Thr86/398 causes its dissociation from the mTORC2 complex, inhibiting mTORC2s kinase activity.
  • Immunogen
    A recombinant protein fragment from the C-terminal region of human SIN1 was used as the immunogen for this antibody.
  • Storage
    Aliquot and store frozen at -20oC or colder to avoid repeated freeze-thaw cycles.
  • Gene target
    SIN1
    • Gene info
  • Gene symbol
    MAPKAP1
  • isotype filter
    • Rabbit IgG
  • technique filter
    • Antibody
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Alternative technique
    antibodies