- Catalog numberF50172-0.4ML
- Product nameRIPK3 Antibody
- Size0.4 ml
- PriceAsk For Price
- Short nameAnti-RIPK3
- CategoryAntibody
- ConcentrationIn 1X PBS, pH 7.4, with 0.09% sodium azide
- FormPurified
- ConjugationUnconjugated
- ClonePolyclonal antibody
- Recognised antigenRIPK3
- Host animalRabbit (Oryctolagus cuniculus)
- ClonalityPolyclonal (rabbit origin)
- IsotypeRabbit Ig
- Species reactivityHuman (Homo sapiens), Mouse (Mus musculus) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
- Tested applicationsIHC, WB, ELISA
- Recommended dilutionsWestern blot: 1:1000,IHC (Paraffin): 1:10-1:50
- NotesTitration of the RIPK3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
- Intented useThis RIPK3 antibodyis to be used only for research purposes and not for diagnostics..
- UniprotQ9Y572
- PurityPurified
- DescriptionThe product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.
- ImmunogenA portion of amino acids 61-91 from the human protein was used as the immunogen for this RIPK3 antibody.
- StorageAliquot the RIPK3 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
- Alternative to gene target
- [ "receptor-interacting serine-threonine kinase 3", "RIP3", "RIPK3 and IDBG-3902 and ENSG00000129465 and 11035", "transferase activity", "Plasma membranes", "Ripk3 and IDBG-165974 and ENSMUSG00000022221 and 56532", "RIPK3 and IDBG-645676 and ENSBTAG00000018422 and 100850132,507427" ]
- Gene targetRIPK3
- Identity:HGNC:10021
- Gene:RIPK3
- Long gene name:receptor interacting serine/threonine kinase 3
- Synonyms gene name:receptor-interacting serine-threonine kinase 3
- Synonyms:RIP3
- Discovery year:1999-12-17
- Entrez gene record:11035
- Pubmed identification:10339433, 10358032
- RefSeq identity:NM_006871
- VEGA ID:OTTHUMG00000029349
- Gene symbolRIPK3
- isotype filter
- Rabbit Ig
- technique filter
- Antibody
- TechniqueAntibody, antibodies against human proteins, antibodies for
- Alternative techniqueantibodies