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Phosphorylated-SOX2 Antibody (pS251)

  • Catalog number
    F48642-0.4ML
  • Product name
    Phosphorylated-SOX2 Antibody (pS251)
  • Size
    0.4 ml
  • Short name
    Anti-Phosphorylated-SOX2 (pS251)
  • Category
    Antibody
  • Concentration
    In 1X PBS, pH 7.4, with 0.09% sodium azide
  • Form
    Antigen affinity purified
  • Conjugation
    Unconjugated
  • Clone
    Polyclonal antibody
  • Recognised antigen
    Phosphorylated-SOX2 (pS251)
  • Host animal
    Rabbit (Oryctolagus cuniculus)
  • Clonality
    Polyclonal (rabbit origin)
  • Isotype
    Rabbit Ig
  • Species reactivity
    Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
  • Tested applications
    DB, ELISA
  • Recommended dilutions
    Dot blot: 1:500
  • Notes
    Titration of the phosphorylated-SOX2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
  • Intented use
    This phosphorylated-SOX2 antibodyis to be used only for research purposes and not for diagnostics..
  • Uniprot
    P48431
  • Purity
    Antigen affinity
  • Description
    This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).
  • Immunogen
    This phosphorylated-SOX2 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS251 of human SOX2.
  • Storage
    Aliquot the phosphorylated-SOX2 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
  • Alternative to gene target
    • [ "SRY (sex determining region Y)-box 2", "ANOP3 and MCOPS3", "SOX2 and IDBG-66692 and ENSG00000181449 and 6657", "protein heterodimerization activity", "nuclei", "Sox2 and IDBG-137912 and ENSMUSG00000074637 and 20674", "SOX2 and IDBG-647279 and ENSBTAG00000011598 and 784383" ]
  • Gene target
    Phosphorylated-SOX2 pS251
    • Gene info
    Locus Specific Databases:LOVDLRG_719
    Gene info
  • Gene symbol
    SOX2, SOX2-OT
  • isotype filter
    • Rabbit Ig
  • technique filter
    • Antibody
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Alternative technique
    antibodies