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Products_type
Recombinant Protein
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Products_short_name
[Inhibitor of nuclear factor kappa-B kinase subunit alpha (Chuk)]
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Other_names
[Inhibitor of nuclear factor kappa-B kinase subunit alpha; Inhibitor of nuclear factor kappa-B kinase subunit alpha; inhibitor of nuclear factor kappa-B kinase subunit alpha; conserved helix-loop-helix ubiquitous kinase; Conserved helix-loop-helix ubiquitous kinase; I-kappa-B kinase 1; IKK1; Nuclear factor NF-kappa-B inhibitor kinase alpha; NFKBIKA]
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Products_gene_name
[Chuk]
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Products_gene_name_syn
[Chuk]
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Other_gene_names
[Chuk; Chuk; IKK1; Ikka; Chuk1; Fbx24; IKBKA; Fbxo24; NFKBIKA; AI256658; IKK alpha; Ikka; I-kappa-B kinase alpha; IKK-A; IKK-alpha; IkBKA; IkappaB kinase; IKK1; NFKBIKA]
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Purity
>85% (SDS-PAGE)
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Form
Lyophilized or liquid (Format to be determined during the manufacturing process)
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Storage_stability
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
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Description
The Recombinant Mouse Inhibitor of factor kappa-B kinase subunit alpha (Chuk) is a α- or alpha protein sometimes glycoprotein present in blood. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
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Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin name
Mus musculus
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Source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
CHUK
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Short name
Recombinant Mouse Inhibitor of factor kappa-B kinase subunit alpha (Chuk)
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Technique
Recombinant, Mouse, mouses, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Host
E Coli or Yeast or Baculovirus or Mammalian Cell
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Species
Mouse, Mouses
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Alternative name
Rec. Mouse suppressor on nuclear factor kappa-B phosphorylation catalyst functionnal sequence a (conserved helix-loop-helix ubiquitous kinase)
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Alternative technique
rec, murine
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Alternative to gene target
conserved helix-loop-helix ubiquitous kinase, IKBKA and IKK-alpha and IKK1 and IKKA and NFKBIKA and TCF16, CHUK and IDBG-243385 and ENSG00000213341 and 1147, transferase activity, nuclei, Chuk and IDBG-169132 and ENSMUSG00000025199 and 12675, CHUK and IDBG-638708 and ENSBTAG00000007591 and 281073
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