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Products_type
Antibody
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Products_short_name
[GDF15]
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Products_name_syn
[Anti-GDF15 Antibody (clone 6D12.H10.E4) IHC-plus; GDF15; MIC1; MIC-1; NAG-1; NRG-1; NSAID-regulated gene 1 protein; PLAB; NSAID-activated gene 1 protein; Placental TGF-beta; PTGFB; GDF-15; PTGF-beta; Human GDF15]
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Other_names
[growth/differentiation factor 15; Growth/differentiation factor 15; growth/differentiation factor 15; NRG-1; PTGF-beta; placental TGF-beta; NSAID-activated gene 1 protein; NSAID-regulated gene 1 protein; prostate differentiation factor; macrophage inhibitory cytokine 1; placental bone morphogenetic protein; NSAID (nonsteroidal anti-inflammatory drug)-activated protein 1; growth differentiation factor 15; Macrophage inhibitory cytokine 1; MIC-1; NSAID-activated gene 1 protein; NAG-1; NSAID-regulated gene 1 protein; NRG-1; Placental TGF-beta; Placental bone morphogenetic protein; Prostate differentiation factor]
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Products_gene_name
[GDF15]
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Other_gene_names
[GDF15; GDF15; PDF; MIC1; PLAB; MIC-1; NAG-1; PTGFB; GDF-15; MIC1; PDF; PLAB; PTGFB; GDF-15; MIC-1; NAG-1; NRG-1]
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Clonality
Monoclonal
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Clone
[6D12.H10.E4]
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Reactivity
Chimpanzee, Macaque
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Specificity
This antibody reacts with the C-terminus of endogenous NAG-1 protein from human tissues. A BLAST analysis suggests reactivity with NAG-1 from chimpanzee and macaque based on a 100% homology. Partial reactivity is expected against rat based on an 86% homology with the immunizing sequence. Cross-reactivity with NAG-1 from other sources has not been determined.
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Purity
Protein G Purified chromatography
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Form
0.02 M Potassium Phosphate, pH 7.2, 0.15 M NaCl, 0.01% Sodium Azide.
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Concentration
1 mg/ml
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Storage_stability
Store vial at -20°C prior to opening. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid freeze-thaw cycles. Centrifuge product if not completely clear after standing at room temperature. This product is stable several weeks at 4°C as an undiluted liquid.
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Tested_application
Immunohistochemistry (IHC), Immunohistochemistry-Paraffin (IHC-P), Western Blot (WB), ELISA
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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About
Immunoglobulin gamma, IgG, mouse monoclonal H&L chain clones or rabbit, goat polyclonal antibodies have 4 parts. There are 2 heavy chains, 2 light chains. The IgG antibody has 2 antigen binding sites. They represent 70% or more of serum antibodies. This antibody can be antigen purified or protein A or G purified. For storage sodium azide is added or you can call us to request azide free antibody preparations. These will need colder storage temperatures. Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes. Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
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Latin name
Rattus norvegicus
