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Rat Anti-Mouse CD38-FITC

  • Catalog number
    MBS673338
  • Product name
    Rat Anti-Mouse CD38-FITC
  • Size
    5x0.5 mg
  • Products type
    Antibody
  • Products short name
    [CD38]
  • Products name syn
    [Rat Anti-Mouse CD38 - FITC; Rat Anti-Mouse CD38]
  • Other names
    [CD38; ADP-ribosyl cyclase 1; ADP-ribosyl cyclase 1; cADPr hydrolase 1; CD38 antigen (p45); OTTHUMP00000158633; OTTHUMP00000217743; NAD(+) nucleosidase; cyclic ADP-ribose hydrolase 1; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase; CD38 molecule; Cyclic ADP-ribose hydrolase 1; cADPr hydrolase 1; T10]
  • Other gene names
    [CD38; CD38; T10]
  • Clonality
    Monoclonal
  • Isotype
    Rat IgG2a kappa
  • Clone
    [NIMR-5]
  • Host
    Rat
  • Reactivity
    Mouse
  • Specificity
    CD38, Mr 42-46 kDa Murine CD38, a type II transmembrane glycoprotein, is a bifunctional ectoenzyme capable of catabolizing nicotinamide adenine dinucleotide (NAD+) to cyclic ADP-ribose (cADPR), and then hydrolyzing cADPR to adenosine diphosphoribose (ADPR). It is expressed at high levels on the surface of peripheral B-lineage cells, and at low density on germinal center B cells from unimmunized mice. It has also been reported to be expressed at moderate levels on NK cells, a proportion of peripheral T cells, and a subpopulation of thymocytes which are mostly TCR alpha beta ^+, CD4^-, CD8^-. Murine CD38 is also expressed by all Mac-1^+ macrophages in the peritoneal cavities of unimmunized mice, but not by unstimulated bone-marrow-derived macrophages. Monoclonal antibodies to CD38 have been shown to induce B- and T-cell proliferation, protect B cells from apoptosis, and inhibit B lymphopoiesis.^1-8
  • Form
    Fluorescein (FITC) Conjugate
  • Storage stability
    The purified (UNLB) antibody is supplied as 0.5 mg of purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added. Store at 2-8 degree C. The fluorescein (FITC) conjugate is supplied as 0.5 mg in 1.0 mL of PBS/NaN3. Store at 2-8 degree C. The biotin (BIOT) conjugate is supplied as 0.5 mg in 1.0 mL of PBS/NaN3. Store at 2-8 degree C. The R-phycoerythrin (R-PE) conjugate is supplied as 0.1 mg in 1.0 mL or 0.2 in 2.0 mL of PBS/NaN3 and a stabilizing agent. Store at 2-8 degree C. Do not freeze! The allophycocyanin (APC) conjugate is supplied as as 0.1 mg in 1.0 mL of PBS/NaN3 and a stabilizing agent. Store at 2-8 degree C. Do not freeze! The Spectral Red (SPRD) conjugate is supplied as 0.1 mg in 1.0 mL of PBS/NaN3 and a stabilizing agent. Store at 2-8 degree C. Do not freeze! The low endotoxin, azide-free (LE/AF) antibody is supplied as 0.5 mg purified immunoglobulin in 1.0 mL of PBS. Aliquot and store at or below -20 degree C. Protect conjugated forms from light. Aliquot and freeze the low endotoxin, azide-free product at -20 degree C immediately upon receipt. Each reagent is stable for the period shown on the bottle label if stored as directed.
  • Tested application
    Flow Cytometry; Immunohistochemistry (Frozen Sections); Immunoprecipitation
  • Alternative to gene target
    • [ "CD38 molecule", "ADPRC 1 and T10", "CD38 and IDBG-10668 and ENSG00000004468 and 952", "hydrolase activity", "nuclei", "Cd38 and IDBG-161475 and ENSMUSG00000029084 and 12494", "CD38 and IDBG-643982 and ENSBTAG00000013569 and 327677" ]
  • Gene target
    CD38
    • Gene info
  • Gene symbol
    CD38
  • isotype filter
    • Rat IgG2a kappa
  • Short name
    Anti-Mouse CD38-FITC
  • Label
    FITC
  • label filter
    • FITC
  • technique filter
    • anti-
    • Mouse
    • anti
    • FITC
  • Technique
    anti-, Mouse, anti, FITC, antibody to, antibodies, Fluorescein, mouses
  • Alternative technique
    murine, antibodies, fluorescine