- Catalog numberMBS670156
- Product nameMouse Anti-Human TIMP-4-UNLB
- Size0.1 mg
- PriceAsk For Price
- Products typeAntibody
- Products short name[TIMP-4]
- Products name syn[Mouse Anti-Human TIMP-4 - Purified, Unlabeled Antibody; Mouse Anti-Human TIMP-4]
- Other names[tissue inhibitor of metalloproteinase-4; tissue inhibitor of metalloproteinase-4]
- Other gene names[TIMP-4]
- ClonalityMonoclonal
- IsotypeMouse IgG2a
- Clone[SB30c]
- HostMouse
- ReactivityHuman
- SpecificityHuman TIMP-4 Tissue inhibitors of matrix metalloproteinases (TIMPs) constitute a family of secreted multifunctional proteins which are classified based on structural similarity to each other as well as their ability to inhibit matrix metalloproteinases (MMPs). TIMPs therefore play a critical role in ECM homeostasis but have also been shown to have erythroid-potentiating and cell growth-promoting activities. TIMP-4 (~23kDa), unlike TIMP-1, TIMP-2 and TIMP-3, shows restricted localization to cardiac, neural, breast and muscle tissue. Cardiospecific TIMP-4 seems to play a significant role in regulating the normal cell phenotype since reduced levels elicit cellular transformation. It has been shown to be an inhibitor of MMP-1, MMP- 2, MMP-3, MMP-7 and MMP-9 with a preference for MMP-2 and MMP-7. 1-9
- FormPurified (UNLB) Antibody
- Storage stabilityThe purified antibody (UNLB) is supplied as 0.1 mg purified immunoglobulin in 0.2 mL of 100 mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added. Store at 2-8 degree C. The horseradish peroxidase (HRP) conjugate is supplied as 1.0 mL of stock solution in 50% glycerol/50% PBS, pH 7.4. No preservative added. Store at 2-8 degree C or long-term at -20 degree C. Reagents are stable for the period shown on the label if stored as directed.
- Tested applicationImmunohistochemistry (Frozen Sections); Western Blot
- Gene targetTIMP-4-UNLB
- Identity:HGNC:11820
- Gene:TIMP1
- Long gene name:TIMP metallopeptidase inhibitor 1
- Synonyms gene name:tissue inhibitor of metalloproteinase 1 (erythroid potentiating activity, collagenase inhibitor)
- Synonyms:EPO
- Discovery year:1986-01-01
- Entrez gene record:7076
- RefSeq identity:NM_003254
- Classification:Tissue inhibitor of metallopeptidases
- VEGA ID:OTTHUMG00000021447
- Identity:HGNC:35296
- Gene:MIR1302-4
- Long gene name:microRNA 1302-4
- Synonyms:hsa-mir-1302-4
- Discovery year:2008-11-03
- Entrez gene record:100302130
- RefSeq identity:NR_031633
- Classification:MicroRNA MIR1302 family
- Identity:HGNC:37522
- Gene:PIRC18
- Long gene name:piwi-interacting RNA cluster 18
- Discovery year:2009-11-05
- Entrez gene record:100313906
- Pubmed identification:17881367
- Classification:Piwi-interacting RNA clusters
- Identity:HGNC:37520
- Gene:PIRC16
- Long gene name:piwi-interacting RNA cluster 16
- Discovery year:2009-11-05
- Entrez gene record:100313849
- Pubmed identification:17881367
- Classification:Piwi-interacting RNA clusters
- Identity:HGNC:32992
- Gene:SNORD114-4
- Long gene name:small nucleolar RNA, C/D box 114-4
- Synonyms:14q(II-4)
- Discovery year:2006-09-26
- Entrez gene record:767580
- Pubmed identification:12045206
- RefSeq identity:NR_003196.1
- Classification:Small nucleolar RNAs, C/D box
- Identity:HGNC:5809
- Gene:IGKV2OR2-4
- Long gene name:immunoglobulin kappa variable 2/OR2-4 (pseudogene)
- Synonyms gene name:immunoglobulin kappa variable 2/OR2-4, immunoglobulin kappa variable 2/OR2-4 pseudogene
- Synonyms:IGKV2/OR2-4,
- Discovery year:2000-04-18
- Entrez gene record:28858
- Pubmed identification:2111145
- Classification:Immunoglobulin kappa (IGK) orphons
- Identity:HGNC:33687
- Gene:MIR941-4
- Long gene name:microRNA 941-4
- Synonyms:hsa-mir-941-4
- Discovery year:2007-10-24
- Entrez gene record:100126330
- RefSeq identity:NR_040032
- Classification:MicroRNAs
- Identity:HGNC:37523
- Gene:PIRC19
- Long gene name:piwi-interacting RNA cluster 19
- Discovery year:2009-11-05
- Entrez gene record:100313926
- Pubmed identification:17881367
- Classification:Piwi-interacting RNA clusters
- Gene symbolTIMP1, MIR1302-4, PIRC18, PIRC16, SNORD114-4, IGKV2OR2-4, MIR941-4, PIRC19
- isotype filter
- Mouse IgG2a
- Short nameMouse Anti- TIMP-4-UNLB
- technique filter
- anti-Human
- anti-
- Mouse
- anti
- Techniqueanti-Human, anti-, Mouse, anti, antibody to, antibodies, antibodies against human proteins, mouses
- Alternative techniquemurine, antibodies
Gene info
Locus Specific Databases:Global Variome shared LOVD