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Mouse Anti-Human TIMP-4-UNLB

  • Catalog number
    MBS670156
  • Product name
    Mouse Anti-Human TIMP-4-UNLB
  • Size
    0.1 mg
  • Products type
    Antibody
  • Products short name
    [TIMP-4]
  • Products name syn
    [Mouse Anti-Human TIMP-4 - Purified, Unlabeled Antibody; Mouse Anti-Human TIMP-4]
  • Other names
    [tissue inhibitor of metalloproteinase-4; tissue inhibitor of metalloproteinase-4]
  • Other gene names
    [TIMP-4]
  • Clonality
    Monoclonal
  • Isotype
    Mouse IgG2a
  • Clone
    [SB30c]
  • Host
    Mouse
  • Reactivity
    Human
  • Specificity
    Human TIMP-4 Tissue inhibitors of matrix metalloproteinases (TIMPs) constitute a family of secreted multifunctional proteins which are classified based on structural similarity to each other as well as their ability to inhibit matrix metalloproteinases (MMPs). TIMPs therefore play a critical role in ECM homeostasis but have also been shown to have erythroid-potentiating and cell growth-promoting activities. TIMP-4 (~23kDa), unlike TIMP-1, TIMP-2 and TIMP-3, shows restricted localization to cardiac, neural, breast and muscle tissue. Cardiospecific TIMP-4 seems to play a significant role in regulating the normal cell phenotype since reduced levels elicit cellular transformation. It has been shown to be an inhibitor of MMP-1, MMP- 2, MMP-3, MMP-7 and MMP-9 with a preference for MMP-2 and MMP-7. 1-9
  • Form
    Purified (UNLB) Antibody
  • Storage stability
    The purified antibody (UNLB) is supplied as 0.1 mg purified immunoglobulin in 0.2 mL of 100 mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added. Store at 2-8 degree C. The horseradish peroxidase (HRP) conjugate is supplied as 1.0 mL of stock solution in 50% glycerol/50% PBS, pH 7.4. No preservative added. Store at 2-8 degree C or long-term at -20 degree C. Reagents are stable for the period shown on the label if stored as directed.
  • Tested application
    Immunohistochemistry (Frozen Sections); Western Blot
  • Gene target
    TIMP-4-UNLB
    • Gene info
    Locus Specific Databases:Global Variome shared LOVD
    Gene info
    Gene info
    • Identity:HGNC:37522
    • Gene:PIRC18
    • Long gene name:piwi-interacting RNA cluster 18
    • Discovery year:2009-11-05
    • Entrez gene record:100313906
    • Pubmed identification:17881367
    • Classification:Piwi-interacting RNA clusters
    Gene info
    • Identity:HGNC:37520
    • Gene:PIRC16
    • Long gene name:piwi-interacting RNA cluster 16
    • Discovery year:2009-11-05
    • Entrez gene record:100313849
    • Pubmed identification:17881367
    • Classification:Piwi-interacting RNA clusters
    Gene info
    Gene info
    Gene info
    Gene info
    • Identity:HGNC:37523
    • Gene:PIRC19
    • Long gene name:piwi-interacting RNA cluster 19
    • Discovery year:2009-11-05
    • Entrez gene record:100313926
    • Pubmed identification:17881367
    • Classification:Piwi-interacting RNA clusters
  • Gene symbol
    TIMP1, MIR1302-4, PIRC18, PIRC16, SNORD114-4, IGKV2OR2-4, MIR941-4, PIRC19
  • isotype filter
    • Mouse IgG2a
  • Short name
    Mouse Anti- TIMP-4-UNLB
  • technique filter
    • anti-Human
    • anti-
    • Mouse
    • anti
  • Technique
    anti-Human, anti-, Mouse, anti, antibody to, antibodies, antibodies against human proteins, mouses
  • Alternative technique
    murine, antibodies