- Catalog numberMBS670016
- Product nameMouse Anti-Cytokeratin 18-BIOT
- Size5x0.1 mg
- PriceAsk For Price
- Products typeAntibody
- Products short name[Cytokeratin 18]
- Products name syn[Mouse Anti-Cytokeratin 18 - Biotin; Mouse Anti-Cytokeratin 18]
- Other names[cytokeratin 18; Keratin, type I cytoskeletal 18; keratin, type I cytoskeletal 18; CK-18; keratin-18; cytokeratin 18; cytokeratin-18; cell proliferation-inducing protein 46; cell proliferation-inducing gene 46 protein; keratin 18; Cell proliferation-inducing gene 46 protein; Cytokeratin-18; CK-18; Keratin-18]
- Other gene names[KRT18; KRT18; K18; CYK18; CYK18]
- ClonalityMonoclonal
- IsotypeMouse (BALB/c) IgG2b
- Clone[SB38b1]
- HostMouse
- SpecificityKeratin 18 (48 kDa)1 Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1-8). The two keratin types share only 30% sequence homology.2-6 Keratins demonstrate tissue- and differentiation-specific expression profiles. Cytokeratin 18, also known as keratin 18, is a type I intermediate filament protein of approximately 48 kDa. It exists as a heterotetramer composed of two type I and two type II keratins. Cytokeratin 18 is expressed in all simple type epithelia and basal cells of many squamous and non-epidermal epithelia, and is often co-expressed with cytokeratin 8.7-9 Tissues from the gastrointestinal tract, respiratory tract and urogenital tract, as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18. The SB38b monoclonal antibody reacts specifically with keratin 18 and recombinant N-terminal keratin 18.
- FormBiotin (BIOT) Conjugate
- Storage stabilityThe purified (UNLB) antibody is supplied as 0.1 mg purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.2; store at 2-8 degree C. The fluorescein (FITC) conjugate is supplied as 0.1 mg in 0.2 mL PBS/NaN3. Store at 2-8 degree C. The horseradish peroxidase (HRP) conjugate is supplied as 1.0 mL of stock solution in 50% glycerol/50% PBS, pH 7.4. No preservative added. Store at 2-8 degree C or long-term at -20 The biotin (BIOT) conjugate is supplied as 0.1 mg in 0.2 mL PBS/NaN3. Store at 2-8 degree C.
- Tested applicationELISA; Immunohistochemistry; Western Blot
- Gene targetCytokeratin 18-BIOT
- Identity:HGNC:33006
- Gene:SNORD114-18
- Long gene name:small nucleolar RNA, C/D box 114-18
- Synonyms:14q(II-18)
- Discovery year:2006-09-26
- Entrez gene record:767596
- Pubmed identification:12045206
- RefSeq identity:NR_003211.1
- Classification:Small nucleolar RNAs, C/D box
- Identity:HGNC:37600
- Gene:PIRC96
- Long gene name:piwi-interacting RNA cluster 96
- Discovery year:2009-11-05
- Entrez gene record:100313800
- Pubmed identification:17881367
- Classification:Piwi-interacting RNA clusters
- Identity:HGNC:33084
- Gene:SNORD116-18
- Long gene name:small nucleolar RNA, C/D box 116-18
- Synonyms:HBII-85-18
- Discovery year:2007-02-15
- Entrez gene record:100033430
- Pubmed identification:11106375, 11726556
- RefSeq identity:NR_003333
- Classification:Small nucleolar RNAs, C/D box
- Identity:HGNC:5889
- Gene:IGLV2-18
- Long gene name:immunoglobulin lambda variable 2-18
- Discovery year:2000-05-08
- Entrez gene record:28814
- RefSeq identity:NG_000002
- Classification:Immunoglobulin lambda locus at 22q11.2
- VEGA ID:OTTHUMG00000151232
- Identity:HGNC:5549
- Gene:IGHV1-18
- Long gene name:immunoglobulin heavy variable 1-18
- Discovery year:2000-04-04
- Entrez gene record:28468
- RefSeq identity:NG_001019
- Classification:Immunoglobulin heavy locus at 14q32.33
- VEGA ID:OTTHUMG00000152276
- Identity:HGNC:33037
- Gene:SNORD115-18
- Long gene name:small nucleolar RNA, C/D box 115-18
- Synonyms:HBII-52-18
- Discovery year:2007-02-15
- Entrez gene record:100033456
- Pubmed identification:11106375, 11726556
- RefSeq identity:NR_003310.1
- Classification:Small nucleolar RNAs, C/D box
- Identity:HGNC:49306
- Gene:ERVW-18
- Long gene name:endogenous retrovirus group W member 18
- Synonyms gene name:endogenous retrovirus group W, member 18
- Discovery year:2013-10-21
- Identity:HGNC:5794
- Gene:IGKV2D-18
- Long gene name:immunoglobulin kappa variable 2D-18 (pseudogene)
- Synonyms gene name:immunoglobulin kappa variable 2D-18, immunoglobulin kappa variable 2D-18 pseudogene
- Discovery year:2000-04-18
- Entrez gene record:28888
- RefSeq identity:NG_000833
- Classification:Immunoglobulin kappa locus at 2p11.2
- VEGA ID:OTTHUMG00000151620
- Identity:HGNC:5778
- Gene:IGKV2-18
- Long gene name:immunoglobulin kappa variable 2-18 (pseudogene)
- Synonyms gene name:immunoglobulin kappa variable 2-18, immunoglobulin kappa variable 2-18 pseudogene
- Discovery year:2000-04-18
- Entrez gene record:28926
- RefSeq identity:NG_000834
- Classification:Immunoglobulin kappa locus at 2p11.2
- VEGA ID:OTTHUMG00000151644
- Gene symbolSNORD114-18, PIRC96, SNORD116-18, IGLV2-18, IGHV1-18, SNORD115-18, ERVW-18, IGKV2D-18, IGKV2-18
- isotype filter
- Mouse BALB c IgG2b
- Short nameMouse Anti-Cytokeratin 18-BIOT
- technique filter
- anti-
- Mouse
- anti
- Techniqueanti-, Mouse, anti, antibody to, antibodies, mouses
- Alternative techniquemurine, antibodies